Atovaquone, chloroquine, primaquine, quinine and tetracycline: antiproliferative effects of relevant antimalarials on Neospora caninum.

Author: AbichabkiNathália de Lima Martins, Abreu-FilhoPéricles Gama, BaroniLuciana, BrochiJade Cabestre Venancio, PereiraLuiz Miguel, YatsudaAna Patrícia, de LucaGabriela

Paper Details 
Original Abstract of the Article :
Neospora caninum is an apicomplexan parasite that causes abortion in cattle, resulting in significant economic losses. There is no commercial treatment for neosporosis, and drug repositioning is a fast strategy to test possible candidates against N. caninum. In this article, we describe the effects ...See full text at original site
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引用元:
https://doi.org/10.1590/S1984-29612021006

データ提供:米国国立医学図書館(NLM)

Repurposing Antimalarials: A Potential Weapon Against Neospora caninum

The field of parasitic infections is a vast and challenging desert, with researchers continually searching for new ways to combat these resilient organisms. This study focuses on the potential of repurposing existing antimalarial drugs for treating neosporosis, a disease caused by the parasite *Neospora caninum*. It's like finding a hidden oasis in the desert of parasitic research, where existing resources can be used to address a new challenge. The authors are investigating the effects of various antimalarial drugs on the proliferation of *Neospora caninum*, hoping to identify potential treatment options.

A New Path to Victory: Repurposing Drugs for Neosporosis Treatment

The study suggests that certain antimalarial drugs, such as atovaquone and tetracycline, show promise against *Neospora caninum*. It's like finding a new route through the desert, leading to a potential solution for neosporosis. This finding opens up new possibilities for treating this debilitating disease, particularly in livestock, where it can cause significant economic losses. Further research is needed to confirm these findings and optimize treatment strategies.

Navigating Parasitic Infections: A Continuous Quest for Solutions

This research emphasizes the importance of exploring new avenues for combating parasitic infections. It's like a camel adapting its strategies to survive in a harsh desert environment. Repurposing existing drugs and exploring novel approaches can help us develop more effective treatments for these stubborn parasites. Let's continue to invest in research and development to find lasting solutions to the challenges posed by parasitic infections.

Dr.Camel's Conclusion

This study offers a new perspective on combating parasitic infections, suggesting that existing drugs could be repurposed to target *Neospora caninum*. Like a camel navigating a challenging desert, researchers are continually seeking creative solutions to overcome obstacles and find new pathways to victory. The quest for effective treatments against parasitic diseases continues, and every new discovery brings us closer to a future where these infections are no longer a threat.

Date :
  1. Date Completed 2021-04-08
  2. Date Revised 2021-04-08
Further Info :

Pubmed ID

33787719

DOI: Digital Object Identifier

10.1590/S1984-29612021006

Related Literature

SNS
PICO Info
in preparation
Languages

English

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