Grape seed extract improved the fertility-enhancing effect of atorvastatin in high-fat diet-induced testicular injury in rats: involvement of antioxidant and anti-apoptotic effects.

Author: Abd El-AalRania A, Abdel-LatifHekma A, AbdelkaderNoha F, AbdulwahabDalia K, IbrahimWeam W

Paper Details 
Original Abstract of the Article :
Reduced male fertility is highly prevalent with hypercholesterolaemia. Though statins are drugs of choice for hypercholesterolaemia, their effect on male fertility is still controversial and dose-dependent. Grape seed extract (GSE) possess hypocholesterolemic and testicular protective effects. Thus,...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1093/jpp/rgaa002

データ提供:米国国立医学図書館(NLM)

Grape Seed Extract and Atorvastatin: A Powerful Combination for Male Fertility?

In the vast desert of reproductive health, navigating infertility can be a challenging journey. This study investigates the effects of atorvastatin, a cholesterol-lowering medication, on male fertility and explores the potential benefits of combining it with grape seed extract (GSE). The researchers found that low-dose atorvastatin, when combined with GSE, exhibited a positive effect on male fertility in rats with high cholesterol levels. This combination seemed to counteract the negative impacts of high cholesterol on testicular health, leading to improved fertility outcomes.

A New Approach to Male Fertility

The study suggests that a combination of low-dose atorvastatin and GSE may be a valuable tool for improving male fertility in individuals with high cholesterol levels. This approach offers a potential solution for addressing a common issue that can contribute to fertility challenges.

Taking Care of Your Reproductive Health

Maintaining overall health, including managing cholesterol levels, is crucial for optimal reproductive health. Consulting with a healthcare professional is essential to discuss individual needs and determine the most appropriate approach to managing fertility-related concerns.

Dr.Camel's Conclusion

This study sheds light on the potential of combining atorvastatin and GSE to improve male fertility. Further research is needed to confirm these findings and explore the best way to apply this approach in clinical settings.

Date :
  1. Date Completed 2021-11-04
  2. Date Revised 2021-11-04
Further Info :

Pubmed ID

33793875

DOI: Digital Object Identifier

10.1093/jpp/rgaa002

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.