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[Bempedoic Acid].

Author: El-ArmoucheAli, KünzelStephan R, LeefmannJulian, SchmidtMichael M, WagnerMichael

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Bempedoic acid is a new cholesterol-lowering drug that selectively inhibits ATP-Citrate-Lyase, a key enzyme in cholesterol biosynthesis. This drug has shown promising results in reducing LDL cholesterol levels without the muscle-related side effects associated with other cholesterol-lowering therapies.
Paper Details　
Original Abstract of the Article :
ATP-Citrate-Lyase is a key enzyme of cholesterol biosynthesis. Its liver-specific inhibition by the bempedoic acid opens new possibilities to effectively escalate a cholesterol-lowering therapy while avoiding muscle-related side effects. Herein, we present the properties of this new first-in-class p...See full text at original site
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引用元：
https://doi.org/10.1055/a-1136-4356

データ提供：米国国立医学図書館（NLM）

Bempedoic Acid

This research delves into the fascinating world of cholesterol, a vital component of our cells but also a culprit in cardiovascular disease. Imagine a camel traversing the desert with a heavy load – too much cholesterol can weigh down the body's systems. This study focuses on a new drug, bempedoic acid, which targets a key enzyme in cholesterol biosynthesis.

A promising new approach to cholesterol management

This research highlights the potential of bempedoic acid in lowering cholesterol levels. Just as a skilled caravan leader strategically plans a route to avoid difficult terrain, this drug effectively targets the specific process responsible for cholesterol production. This new approach aims to improve cholesterol management while minimizing potential muscle-related side effects.

Optimizing cholesterol levels for better health

This study provides hope for individuals struggling with high cholesterol levels. Imagine a camel caravan reaching its destination with a lighter load and greater ease. This research suggests that bempedoic acid may offer a safe and effective way to manage cholesterol, potentially improving cardiovascular health and overall well-being.

Dr.Camel's Conclusion

This research showcases the innovative potential of bempedoic acid in managing cholesterol levels. Just like a skilled camel caravan navigating a desert, this drug offers a new path to achieve better health and well-being by effectively targeting the underlying mechanisms of cholesterol production.
Date :
  1. Date Completed 2021-10-20
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

33853173

DOI: Digital Object Identifier

10.1055/a-1136-4356

Related Literature

Article Analysis
・Side Effects of bempedoic acid
SNS
PICO Info
in preparation
Languages

German

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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