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Substance use, Unlike Dolutegravir, is Associated with Mood Symptoms in People Living with HIV.

Author: NeteaMihai, SchellekensArnt, Van de WijerLisa, de MastQuirijn, van VerseveldMike, van der HeijdenWouter, van der VenAndré

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study compared mood, anxiety, impulsivity, and substance use in dolutegravir-treated and dolutegravir-naive people living with HIV (PLHIV). The study found no association between dolutegravir use and neuropsychiatric side effects, highlighting the importance of addressing mental health and substance use issues in this population.
Paper Details　
Original Abstract of the Article :
Contradictory data have been reported concerning neuropsychiatric side effects of the first-line antiretroviral drug dolutegravir, which may be partly due to lack of control groups or psychiatric assessment tools. Using validated self-report questionnaires, we compared mood and anxiety (DASS-42), im...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602138/

データ提供：米国国立医学図書館（NLM）

Substance Use, Not Dolutegravir, is Associated with Mood Symptoms in People Living with HIV

The field of HIV research is constantly seeking to improve the lives of individuals living with this chronic condition. This research explores the neuropsychiatric side effects of dolutegravir, a widely used antiretroviral drug, examining its potential impact on mood and anxiety. The authors compared mood, anxiety, impulsivity, and substance use in dolutegravir-treated and dolutegravir-naive individuals living with HIV. While they found no significant differences between the two groups, the study revealed a strong association between substance use and mood symptoms, specifically depression and stress, in individuals living with HIV.

The Impact of Substance Use on Mood in People Living with HIV

This study highlights the significant role of substance use in contributing to mood symptoms in individuals living with HIV. The findings suggest that addressing substance use issues may be crucial for improving mental health outcomes in this population.

Navigating the Challenges of HIV Treatment

Living with HIV presents numerous challenges, including the potential for mental health complications. This research underscores the importance of addressing substance use and mental health concerns in individuals living with HIV to improve their overall well-being.

Dr. Camel's Conclusion

Just as a camel must navigate a challenging desert landscape, individuals living with HIV face a variety of obstacles, including the potential for mental health challenges. This study emphasizes the importance of addressing substance use and mental health concerns to help individuals living with HIV thrive and lead fulfilling lives.

Date :
  1. Date Completed 2021-11-22
  2. Date Revised 2022-02-18
Further Info :

Pubmed ID

33903997

DOI: Digital Object Identifier

PMC8602138

Related Literature

Article Analysis
・Side Effects of dolutegravir
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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