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Plasma levels, heart rate, and blood pressure after intravenous, oral, and aerosol administration of reproterol in man.
Author: GrevingJ E, HagemanR J, KoëterG H, KrannJ J, de ZeeuwR A
Original Abstract of the Article :
Three healthy volunteers received single doses of reproterol (D 1959) by means of intravenous infusion, oral and aerosol application, respectively. Administrations were separated by at least 1 week. Plasma levels were measured by means of high performance liquid chromatography. After infusion, plasm...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
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引用元:
https://doi.org/10.1002/bod.2510090308
データ提供:米国国立医学図書館(NLM)
Reproterol: Exploring the Pharmacokinetic Landscape of a Potential Bronchodilator
The search for effective treatments for respiratory conditions, such as asthma, continues to be a priority in medicine. This study examines the pharmacokinetic profile of reproterol, a potential bronchodilator, after administration by different routes: intravenous infusion, oral, and aerosol. The authors meticulously investigated the drug's absorption, distribution, and elimination patterns, providing valuable data for understanding its potential therapeutic application.
Reproterol: A Journey Through the Body
The study demonstrates that reproterol exhibits rapid distribution after intravenous infusion, reaching peak plasma levels within minutes. However, the drug's elimination is also rapid, with plasma levels declining quickly. Oral administration resulted in a more sustained plasma concentration, while aerosol administration led to low but detectable plasma levels.
Navigating the Sands of Respiratory Health: A Guide for Patients
This research provides valuable insights into the pharmacokinetic profile of reproterol, a potential bronchodilator. Further research is needed to evaluate its efficacy and safety in treating respiratory conditions, but the study provides a solid foundation for understanding the drug's behavior within the body.
Dr.Camel's Conclusion
Reproterol, like a camel traveling across the desert, journeys through the body, leaving its mark in different ways depending on the mode of administration. This study provides a detailed roadmap for understanding the drug's pharmacokinetics, paving the way for future investigations into its potential therapeutic applications.
Date :
- Date Completed 1988-09-08
- Date Revised 2019-10-22
Further Info :
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English
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