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Benefit of adjuvant chemotherapy in patients with special histology subtypes of triple-negative breast cancer: a systematic review.

Author: CriscitielloC, CuriglianoG, D'amicoP, EspositoA, FerraroE, GiuglianoF, MarraA, TrapaniD, UlianoJ, VialeG, ZiaV A A

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This review examines the evidence for adjuvant treatments for triple-negative breast cancer (TNBC), a subtype traditionally associated with poorer prognosis. TNBC special histology subtypes exhibit unique clinical and molecular characteristics and varying responses to antineoplastic treatments. However, no consensus exists on the optimal adjuvant therapy.
Paper Details　
Original Abstract of the Article :
Breast cancer (BC) is a leading cause of morbidity, disability, and mortality in women, worldwide; triple-negative BC (TNBC) is a subtype traditionally associated with poorer prognosis. TNBC special histology subtypes present distinct clinical and molecular features and sensitivity to antineoplastic...See full text at original site
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引用元：
https://doi.org/10.1007/s10549-021-06259-8

データ提供：米国国立医学図書館（NLM）

Triple-Negative Breast Cancer: A Quest for Personalized Treatment

Triple-negative breast cancer (TNBC) is a particularly aggressive subtype of the disease, often associated with a poorer prognosis. This research delves into the complex landscape of TNBC, exploring the distinct features of special histology subtypes and their responsiveness to different antineoplastic treatments. The study aims to provide evidence-based recommendations for the most effective adjuvant therapy for TNBC subtypes.

Tailoring the Treatment: Navigating the Diverse Landscape of TNBC

The study underscores the importance of personalized treatment strategies for TNBC, recognizing that different subtypes may respond differently to various therapies. This highlights the need for a precise diagnosis and a comprehensive understanding of the specific characteristics of each subtype to guide treatment decisions. The research emphasizes the need for further research to refine treatment guidelines for TNBC, ensuring patients receive the most effective and tailored care.

Navigating the Desert of Uncertainty: Finding the Right Path for TNBC Treatment

This research serves as a guidepost for healthcare providers navigating the complex and challenging landscape of TNBC. It emphasizes the need for personalized treatment strategies, recognizing the diversity of TNBC subtypes and their unique responses to therapy. Just as a traveler in a desert needs to carefully choose their route, clinicians must carefully consider the individual characteristics of each patient to determine the most effective treatment approach.

Dr.Camel's Conclusion

This research underscores the complexities of TNBC and the importance of personalized treatment approaches. By delving into the unique features of different subtypes, we can better understand their responses to therapy and tailor treatment strategies to individual needs. This research serves as a valuable resource for healthcare professionals, guiding them in their quest to provide the most effective and individualized care for patients battling TNBC.

Date :
  1. Date Completed 2021-06-23
  2. Date Revised 2021-06-23
Further Info :

Pubmed ID

34043122

DOI: Digital Object Identifier

10.1007/s10549-021-06259-8

Related Literature

Article Analysis
・Effective treatment of breast cancer
SNS
PICO Info
in preparation
Languages

English

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