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Is Allodynia a Determinant Factor in the Effectiveness of Transcranial Direct Current Stimulation in the Prophylaxis of Migraine?

Author: AksuSerkan, BaykanBetül, Cerrahoğlu ŞirinTuba, Hasirci BayirBuse Rahime, KaramürselSacit, KurtAdnan, UlukanÇağrı

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Allodynia, a condition where things that shouldn't cause pain, like a light touch, do cause pain, is a sign of heightened nerve sensitivity. It can make migraine more difficult to treat and increases the risk of chronic migraines. While there are medications, they can have side effects. Transcranial direct current stimulation (tDCS), a non-invasive brain stimulation technique, is being explored as a possible way to prevent migraines.
Paper Details　
Original Abstract of the Article :
Allodynia, the clinical marker of central sensitization, affects even simple daily living activities and increases the tendency for migraine to be more resistant to treatment and have a chronic course. Migraine that impairs quality of life can often be treated with variable pharmaceutical agents, bu...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/34058041

データ提供：米国国立医学図書館（NLM）

Allodynia and Transcranial Direct Current Stimulation for Migraine Prophylaxis

Managing [migraine headaches] can be a challenging task. This study investigates the role of [allodynia], a marker of [central sensitization], in the effectiveness of [transcranial direct current stimulation (tDCS)] for [migraine prophylaxis]. The researchers explore the potential relationship between allodynia and tDCS efficacy, considering the impact of central sensitization on migraine severity and treatment response.

Central Sensitization and Migraine Treatment

The study highlights the complex interplay between [allodynia] and [migraine treatment]. The presence of allodynia, indicative of central sensitization, could influence the effectiveness of tDCS in preventing migraine attacks. Understanding this relationship could help clinicians better predict treatment outcomes and tailor treatment strategies based on individual patient characteristics.

Finding Relief from Migraines

Just as a camel navigates a desert landscape, individuals with migraine headaches face a constant journey of managing their symptoms. This study delves into the intricacies of migraine pathogenesis, exploring the role of central sensitization and its impact on treatment response. By understanding these factors, we can potentially develop more effective and personalized treatment approaches for migraine headaches.

Dr.Camel's Conclusion

Migraine headaches can be a debilitating experience, like a relentless desert sandstorm. This research explores the potential connection between allodynia and tDCS efficacy in migraine prophylaxis, offering valuable insights into the complex interplay of factors that influence migraine management. Understanding these relationships can help us navigate the path towards more effective and personalized treatments for migraine headaches.

Date :
  1. Date Completed 2021-08-18
  2. Date Revised 2022-05-31
Further Info :

Pubmed ID

34058041

DOI: Digital Object Identifier

S1094-7159(21)06206-1

Related Literature

Article Analysis
・Effective treatment of migraine
SNS
PICO Info
in preparation
Languages

English

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