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Auxiliary liver transplantation for management of acute liver failure in children - Systematic review.

Author: LopesMaria Francelina, PiedadeCláudia, QuadrosJoana

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This systematic review assessed auxiliary partial liver orthotopic transplantation (APOLT) for acute pediatric liver failure (PALF). APOLT offers a potential alternative to liver transplantation (LT) by providing a graft that supports liver function until the native liver recovers, potentially allowing for immunosuppression withdrawal.
Paper Details　
Original Abstract of the Article :
Liver transplantation (LT) remains the standard of care in the treatment of acute pediatric liver failure (PALF) for the replacement of a severely damaged native liver in patients who are unlikely to recover. However, this is burdened by the consequences of long-term immunosuppression. Auxiliary par...See full text at original site
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引用元：
https://doi.org/10.1016/j.trre.2021.100631

データ提供：米国国立医学図書館（NLM）

Auxiliary liver transplantation for management of acute liver failure in children - Systematic review

Acute liver failure (ALF), like a devastating desert storm, can threaten our health. This study, published in 2021, explores the role of auxiliary partial liver orthotopic transplantation (APOLT) in managing ALF in children. The researchers conducted a systematic review of existing literature to assess the effectiveness and safety of this innovative surgical procedure.

APOLT - A Potential Lifeline for Children with ALF

The review suggests that APOLT can be a viable option for managing ALF in children. It's like finding a hidden oasis in the desert, offering hope for a new beginning. The procedure involves transplanting a portion of a donor liver, providing temporary support until the child's own liver can recover. This approach offers a potential alternative to whole liver transplantation, which requires lifelong immunosuppression.

Finding New Solutions for Pediatric Liver Failure

This research highlights the importance of exploring new and innovative approaches to managing ALF in children. It's a reminder that, just as a camel must adapt to the challenging conditions of the desert, we need to be creative and resourceful in finding solutions for complex medical conditions. This study encourages us to continue exploring novel treatments that offer hope for a better future for children with ALF.

Dr.Camel's Conclusion

This systematic review provides valuable insight into the potential benefits of APOLT in managing ALF in children. It represents a significant advance in pediatric liver transplantation, offering a potential lifeline for children facing this life-threatening condition. It's a journey of hope, just like a camel's trek across the vast desert, leading us to new and promising horizons in the fight against disease.

Date :
  1. Date Completed 2021-10-28
  2. Date Revised 2022-05-31
Further Info :

Pubmed ID

34098491

DOI: Digital Object Identifier

10.1016/j.trre.2021.100631

Related Literature

Article Analysis
・Effective treatment of liver transplantation
SNS
PICO Info
in preparation
Languages

English

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