Systematic review and network meta-analysis: efficacy of licensed drugs for abdominal bloating in irritable bowel syndrome with constipation.

Author: BlackChristopher J, FordAlexander C, HoughtonLesley A, LacyBrian E, Lugo-FagundoNahyr Sofía, NelsonAlfred D

Paper Details 
Original Abstract of the Article :
BACKGROUND: Although bloating is a highly prevalent and troublesome symptom in irritable bowel syndrome with constipation (IBS-C), treatment is empirical with no specific guidelines for its management. AIM: To conduct a pairwise and network meta-analysis, using a frequentist approach, of Food and D...See full text at original site
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引用元:
https://doi.org/10.1111/apt.16437

データ提供:米国国立医学図書館(NLM)

Licensed Drugs for IBS-C-Related Bloating: A Treasure Hunt in the Desert of Symptoms

This systematic review and network meta-analysis delves into the treatment of abdominal bloating, a common and often troublesome symptom of irritable bowel syndrome with constipation (IBS-C). Researchers aimed to compare the efficacy of Food and Drug Administration-licensed drugs for IBS-C in relieving abdominal bloating.

Bloating Relief: Finding the Right Oasis in the Desert of IBS-C

The analysis revealed that linaclotide, lubiprostone, tenapanor, and tegaserod were all superior to placebo in reducing abdominal bloating in patients with IBS-C. Linaclotide emerged as the most effective treatment, demonstrating a significant improvement in bloating compared to other drugs. Imagine this as a traveler in the desert, searching for the most refreshing oasis – linaclotide stands out as the most effective remedy for bloating.

Managing IBS-C: Navigating the Desert of Discomfort

This research offers valuable insights into the treatment of IBS-C-related bloating. Linaclotide appears to be a promising option for patients seeking relief, providing hope for individuals struggling with this debilitating symptom. It's a reminder that the desert of digestive disorders can be navigated with the right tools and knowledge, leading to a more comfortable and fulfilling life.

Dr.Camel's Conclusion

This systematic review and network meta-analysis offers valuable guidance for managing IBS-C-related bloating. Linaclotide emerges as a potential oasis in the desert of discomfort, highlighting the importance of evidence-based treatment strategies in the management of this challenging condition.

Date :
  1. Date Completed 2021-08-09
  2. Date Revised 2023-09-18
Further Info :

Pubmed ID

34114657

DOI: Digital Object Identifier

10.1111/apt.16437

Related Literature

SNS
PICO Info
in preparation
Languages

English

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