Efficacy and safety of topical administration of tacrolimus in oral lichen planus: An updated systematic review and meta-analysis of randomized controlled trials.

Author: ChengBin, HuJiaqi, SuZhangci, TaoXiaoan

Paper Details 
Original Abstract of the Article :
BACKGROUND: Symptomatic oral lichen planus is a common chronic T-cell-mediated disorder characterized by pain and inflammation. The meta-analysis aimed to compare and evaluate the effects and safety of tacrolimus for treating patients with symptomatic oral lichen planus. METHODS: A comprehensive li...See full text at original site
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引用元:
https://doi.org/10.1111/jop.13217

データ提供:米国国立医学図書館(NLM)

Topical Tacrolimus for Oral Lichen Planus: A New Path to Treatment

The desert of oral health can be a harsh and unforgiving place, with conditions like oral lichen planus (OLP) causing significant discomfort and pain. This study explores the effectiveness and safety of topical tacrolimus, an immunosuppressant medication, for managing symptomatic OLP. The researchers, like explorers seeking a cure, compared tacrolimus to other treatment options, looking for a safe and effective solution for this challenging condition.

A New Oasis in Oral Lichen Planus Treatment: Exploring the Benefits of Topical Tacrolimus

The study revealed that topical tacrolimus was as effective as corticosteroids in resolving OLP symptoms. The researchers found that while tacrolimus may be more likely to cause mild side effects, it offered a comparable level of symptom relief. This finding is like discovering a hidden oasis in the desert, providing a potentially effective alternative to corticosteroids for OLP treatment.

Navigating the Desert of Oral Health: Seeking Safe and Effective Treatment Options

This study underscores the importance of exploring new and effective treatment options for OLP. The findings suggest that topical tacrolimus, with its comparable effectiveness to corticosteroids and minimal side effects, could be a valuable tool for managing this condition. It encourages further research into the long-term benefits and safety of tacrolimus for OLP treatment.

Dr.Camel's Conclusion

This study offers a promising new avenue for treating oral lichen planus. Topical tacrolimus, with its effectiveness and relatively mild side effects, could provide a valuable alternative to corticosteroids. As we continue to explore the desert of oral health, we must remain vigilant in seeking safe and effective solutions for our patients.

Date :
  1. Date Completed 2022-01-21
  2. Date Revised 2022-01-21
Further Info :

Pubmed ID

34133803

DOI: Digital Object Identifier

10.1111/jop.13217

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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