Therapeutic efficacy of artesunate-amodiaquine and artemether-lumefantrine and polymorphism in Plasmodium falciparum kelch13-propeller gene in Equatorial Guinea.

Author: BerzosaPedro, Edú MayeCorona Eyang, GarciaLuz, Lao SeoaneAngela Katherine, LegrandEric, Mbá AndemeRamona, MenardDidier, NcogoPolicarpo Ricardo, Nsue EsidangSalomón, NtabanganaSpes Caritas, Oki EburiConsuelo, PhiriWonder Philip, Riloha RivasMatilde, RingwaldPascal, WarsameMarian

Paper Details 
Original Abstract of the Article :
Artesunate-amodiaquine (ASAQ) and artemether-lumefantrine (AL) are the currently recommended first- and second-line therapies for uncomplicated Plasmodium falciparum infections in Equatorial Guinea. This study was designed to evaluate the efficacy of these artemisinin-based combinations and detect m...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220721/

データ提供:米国国立医学図書館(NLM)

Evaluating Artemisinin-Based Therapies for Malaria in Equatorial Guinea

This research delves into the fight against malaria, a disease as relentless as the desert sun. The study focuses on Equatorial Guinea, a region facing the challenge of malaria, and evaluates the efficacy of two commonly used anti-malarial treatments. The researchers sought to determine the effectiveness of these treatments and investigate potential genetic mutations in the malaria parasite that might contribute to drug resistance. This investigation is essential to ensure the effectiveness of anti-malarial therapies in the face of evolving parasite populations.

Understanding Malaria Treatment

The study highlights the importance of continuous monitoring and research to ensure the effectiveness of malaria treatment. The researchers' findings provide valuable insights into the complex interplay of drug resistance and genetic mutations in the malaria parasite.

Fighting Malaria

This research emphasizes the importance of ongoing efforts to combat malaria, a disease that continues to pose a significant threat to global health.

Dr.Camel's Conclusion

This research is a reminder of the ongoing battle against malaria, a disease that has plagued humanity for centuries. Just as a desert traveler must be vigilant against the dangers of the harsh environment, researchers must remain alert to the challenges of drug resistance and the need for new and effective treatments. This research shows that the fight against malaria is a journey of constant adaptation and innovation.

Date :
  1. Date Completed 2021-10-05
  2. Date Revised 2021-10-05
Further Info :

Pubmed ID

34158055

DOI: Digital Object Identifier

PMC8220721

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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