Cardiovascular Toxicity of Androgen Deprivation Therapy.

Author: BolandJulia, ChoiWilliam, LeeMaximillian, LinJianqing

Paper Details 
Original Abstract of the Article :
Androgen deprivation therapy (ADT) is the standard of care for the treatment of advanced prostate cancer (PC). ADT, particularly with GnRH agonists, leads to increased risk of cardiovascular disease, including myocardial infarction, hypertension, and stroke. This review discusses the options of ADT,...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254069/

データ提供:米国国立医学図書館(NLM)

Androgen Deprivation Therapy: A Balancing Act in Prostate Cancer

Greetings from Dr. Camel, your guide through the often-complex world of medical treatments. Today, we're exploring the intricate terrain of androgen deprivation therapy (ADT) for prostate cancer. Imagine a delicate ecosystem, where hormones are like the vital forces that keep the balance. ADT disrupts this balance to combat prostate cancer, but like a desert ecosystem, this intervention can have unexpected consequences.

Navigating Side Effects

The researchers highlight a significant risk associated with ADT, particularly with GnRH agonists: an increased risk of cardiovascular disease. Think of it like a drought in a desert ecosystem, the lack of vital hormones can lead to unintended consequences. This study underscores the importance of understanding the potential side effects of ADT and exploring alternative approaches, such as GnRH antagonists, to minimize the risks.

A Balancing Act for Health

The study serves as a crucial reminder of the importance of weighing the benefits and risks of treatment. While ADT can be an effective tool in fighting prostate cancer, it's essential to be aware of the potential cardiovascular risks. For those undergoing ADT, close monitoring and potentially lifestyle modifications may be beneficial to navigate this delicate balance.

Dr. Camel's Conclusion

This research emphasizes the need for a nuanced approach to cancer treatment. Just as a skilled desert guide navigates the landscape carefully, we must consider the potential side effects of therapies. By understanding the delicate balance of our internal ecosystems, we can find more effective and safer ways to combat disease.

Date :
  1. Date Completed 2021-07-12
  2. Date Revised 2021-07-21
Further Info :

Pubmed ID

34216282

DOI: Digital Object Identifier

PMC8254069

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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