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Uterine and Fibroid Imaging Analysis from the FIRSTT Study.

Author: GornyKrzysztof R, HesleyGina K, Laughlin-TommasoShannon K, LemensMaureen A, StewartElizabeth A, VaughanLisa E, WoodrumDavid A

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study compared two treatments for uterine fibroids: uterine artery embolization (UAE) and magnetic resonance imaging-guided focused ultrasound surgery (MRgFUS). Both treatments reduced the size of fibroids by about 50% after 2 and 3 years. While the size of the largest fibroid decreased more with MRgFUS, the overall size of the uterus decreased more with UAE. After 2 years, the amount of non-perfused tissue (tissue without blood flow) was greater in the UAE group. This suggests that both treatments are effective at reducing fibroid size, but the effects on blood flow differ.
Paper Details　
Original Abstract of the Article :
<b><i>Background:</i></b> Women with uterine fibroids often seek uterine-preserving treatments, rather than hysterectomy. Imaging-defined endpoints following nonsurgical treatments for fibroids are limited. <b><i>Materials and Methods:</i></b> Fibroid Interventions: Reducing Symptoms Today and Tomo...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9063146/

データ提供：米国国立医学図書館（NLM）

Fibroid Treatments: Finding the Right Oasis in the Uterine Desert

Dr. Camel here, exploring the world of uterine fibroids. These benign tumors can be a real pain, literally! They often cause discomfort and can even lead to infertility. This study focuses on two minimally invasive treatments for fibroids: uterine artery embolization (UAE) and magnetic resonance imaging-guided focused ultrasound surgery (MRgFUS). The researchers compared the effectiveness of these two approaches in reducing fibroid size and improving symptoms.

UAE and MRgFUS: Similar Effectiveness in Shrinking Fibroids

The study revealed that both UAE and MRgFUS were effective in reducing fibroid size, with similar results observed at 24 and 36 months after treatment. This is good news for patients seeking non-surgical options for managing their fibroids. It's like discovering two different oases in the desert, both offering refreshing relief! However, the study found that UAE resulted in a greater reduction in uterine volume, while MRgFUS led to a greater decrease in the volume of the largest fibroid. This suggests that the choice between UAE and MRgFUS may depend on the specific characteristics of the fibroids and the patient's preferences.

Managing Fibroids: A Journey Through the Uterine Desert

This research highlights the importance of having multiple treatment options available for women with uterine fibroids. It's like discovering a network of oases, each offering a different path through the desert. However, choosing the right treatment requires careful consideration and discussion with a healthcare professional. Understanding the potential benefits and risks of each approach is crucial to making the best decision for individual needs.

Dr. Camel's Conclusion

This study offers valuable insights into the effectiveness of minimally invasive treatments for uterine fibroids. Both UAE and MRgFUS have proven to be effective in reducing fibroid size, but each approach has its unique advantages. It's essential to work with a healthcare professional to determine the best treatment option for your specific situation. Remember, even in the challenging desert of uterine fibroids, there are pathways to relief and improved health!

Date :
  1. Date Completed 2022-04-27
  2. Date Revised 2023-04-02
Further Info :

Pubmed ID

34242085

DOI: Digital Object Identifier

PMC9063146

Related Literature

Article Analysis
・Effective treatment of uterine fibroids
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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