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Cefodizime in serum and skin blister fluid after single intravenous and intramuscular doses in healthy volunteers.

Author: KleselN, KortingH C, MaassL, MutschlerE, Schäfer-KortingM

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Cefodizime, a new cephalosporin antibiotic, was found to be effective in treating gonorrhea when administered intravenously or intramuscularly. Intravenous administration was better tolerated locally.
Paper Details　
Original Abstract of the Article :
In gonorrhea therapy, cephalosporins are conventionally administered by intramuscular (i.m.) injection, which rather frequently leads to local side effects. To investigate whether the well-tolerated intravenous (i.v.) injection of cephalosporins may be of comparable gonocidal effect, levels of cefod...See full text at original site
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引用元：
https://doi.org/10.1128/AAC.31.11.1822

データ提供：米国国立医学図書館（NLM）

Cefodizime: A Promising New Cephalosporin for Gonorrhea

Gonorrhea, a sexually transmitted infection, continues to be a significant public health concern. This study investigates the pharmacokinetics of cefodizime, a new broad-spectrum cephalosporin, in healthy volunteers. The researchers compared the levels of cefodizime in serum and skin blister fluid after intravenous and intramuscular injections.

Cefodizime: Effective and Well-Tolerated

The study demonstrates that cefodizime is well-absorbed after both intravenous and intramuscular administrations, reaching effective concentrations in both serum and skin blister fluid. The results suggest that cefodizime could be a promising new treatment option for gonorrhea, offering similar effectiveness with potentially better tolerability compared to other cephalosporins.

Gonorrhea Treatment: Seeking Effective and Safe Solutions

Gonorrhea can have serious consequences if left untreated. It's essential to seek prompt medical attention if you suspect an infection. This study highlights the importance of ongoing research and development of new and effective treatments for sexually transmitted infections.

Dr.Camel's Conclusion

The study's findings offer a glimmer of hope for individuals battling gonorrhea. Just as a camel adapts to its arid environment, researchers are constantly seeking solutions to the challenges posed by infectious diseases. Cefodizime appears to be a promising new weapon in our arsenal against gonorrhea, potentially offering a more effective and well-tolerated treatment option.

Date :
  1. Date Completed 1988-03-11
  2. Date Revised 2021-05-26
Further Info :

Pubmed ID

3435129

DOI: Digital Object Identifier

10.1128/AAC.31.11.1822

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