Differentiated dosage of microporous colestyramine and its double-blind comparison with a placebo in hypercholesterolaemic patients.

Author: BrunoM, Di PerriT, FranchiM

Paper Details 
Original Abstract of the Article :
A double-blind trial of microporous colestyramine (MPC) at different dosages was undertaken on 18 hypercholesterolaemic patients (Fredrickson classification Type II A) in three groups. During the attack phase of four weeks, three dosage regimens of MPC were used, 9 g, 12 g and 18 g for six patients ...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/3440643

データ提供:米国国立医学図書館(NLM)

Navigating the Desert of Hypercholesterolemia with Colestyramine: A Journey of Dosage

In the vast desert of cardiovascular health, hypercholesterolemia, an excess of cholesterol in the blood, poses a significant threat. Much like a sandstorm, it can create havoc, increasing the risk of heart disease. This study explores the use of microporous colestyramine (MPC), a medication that helps reduce cholesterol levels, as a potential oasis in this desert. The researchers embarked on a double-blind trial, where neither the patients nor the researchers knew who was receiving the medication and who was receiving a placebo (a sugar pill), ensuring a neutral and objective assessment.

Dosage Optimization: Finding the Right Oasis

The study involved 18 patients with hypercholesterolemia. They were divided into three groups, each receiving different doses of MPC. The results showed that all three doses of MPC were effective in lowering cholesterol levels, with minimal side effects. The maintenance phase of the study further confirmed the effectiveness of MPC. The placebo group, on the other hand, showed significant adverse changes in cholesterol levels. This clearly demonstrated the beneficial effects of MPC.

A Oasis for Hypercholesterolemia Management

The study concluded that MPC is a valuable option for managing hypercholesterolemia, especially for individuals who cannot adhere to strict dietary restrictions. Like a refreshing oasis in the desert, MPC can provide relief from the burden of high cholesterol levels, paving the way for a healthier heart. However, as always, consulting a doctor is crucial for determining the appropriate dose and tailoring treatment to individual needs.

Dr.Camel's Conclusion

This study highlights the effectiveness of MPC in managing hypercholesterolemia, offering a much-needed oasis in the desert of cardiovascular health. It underscores the importance of personalized medicine, tailoring treatment to individual needs, and considering MPC as a valuable option for those struggling with high cholesterol. Remember, even in the vast expanse of the desert, there are always oases waiting to be discovered.

Date :
  1. Date Completed 1988-04-18
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

3440643

DOI: Digital Object Identifier

3440643

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SNS
PICO Info
in preparation
Languages

English

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