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Influence of Probiotics on the Development of <i>Clostridioides difficile</i> Infection in Patients Receiving Fluoroquinolones.

Author: BlandChristopher M, JonesBruce M, SheffieldMary E, TerrellBlake, WagnerJamie L

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study evaluated the effect of probiotic supplementation on the development of primary *Clostridioides difficile* infection (CDI) among hospitalized patients receiving fluoroquinolones. The study found that patients who received probiotics had a non-statistically significantly lower incidence of CDI and fewer *C. difficile* diagnostic stool tests performed.
Paper Details　
Original Abstract of the Article :
Fluoroquinolones are associated with an increased risk of <i>Clostridioides difficile</i> infection (CDI). Probiotic supplementation has been shown to reduce the risk of antibiotic-associated diarrhea with variable effects on CDI. The objective of this study was to evaluate receipt of probiotics on ...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396168/

データ提供：米国国立医学図書館（NLM）

Probiotics and Clostridioides difficile infection

Fluoroquinolones, a class of antibiotics, can be lifesavers but also carry a risk of causing a nasty intestinal infection called Clostridioides difficile infection (CDI). This study examines whether probiotics, those friendly bacteria, can help reduce the risk of CDI in patients taking fluoroquinolones. It's like looking for a natural way to protect the delicate balance of the gut while fighting off harmful bacteria.

Probiotics may offer some protection against CDI

The research suggests that probiotics may offer some protection against CDI, but the results were not statistically significant. While this is a promising finding, further research is needed to confirm the effectiveness of probiotics in preventing CDI.

A healthy gut is crucial for overall health

This study highlights the importance of maintaining a healthy gut microbiome, especially when taking antibiotics. Probiotics could potentially play a role in protecting against CDI, but more research is needed to understand their full benefits. Just as a camel relies on its strong and healthy gut to survive in the desert, we need to care for our own gut health to maintain overall well-being.

Dr.Camel's Conclusion

This research takes us on a fascinating journey into the world of the gut microbiome. While the results on probiotics are promising, they remind us that further exploration is needed to fully understand the complex interactions between antibiotics, probiotics, and gut health. It's like venturing deeper into the desert, uncovering new secrets and possibilities for improving our health.

Date :
  1. Date Completed n.d.
  2. Date Revised 2021-08-30
Further Info :

Pubmed ID

34449745

DOI: Digital Object Identifier

PMC8396168

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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