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Therapeutic effects of different polar fractions of hawthorn extract on blood stasis model rats revealed by liquid chromatography-mass spectrometry metabolomics.
Author: LiangShengwang, LuoLan, QiYue, XueQi, ZengLu
Original Abstract of the Article :
Hawthorn, a commonly used traditional Chinese medicine, has been suggested to have therapeutic effects on cardiovascular disease. However, effective fractions of hawthorn extract in the treatment of cardiovascular disease, together with possible therapeutic mechanisms, remain unclear. This study aim...See full text at original site
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引用元:
https://doi.org/10.1002/jssc.202100569
データ提供:米国国立医学図書館(NLM)
Hawthorn Extract: A Promising Remedy for Blood Stasis?
Hawthorn, a plant commonly used in traditional Chinese medicine, is often touted for its therapeutic benefits in cardiovascular health. This study investigates the effects of different polar fractions of hawthorn extract on blood stasis model rats, aiming to identify effective fractions and explore potential metabolic mechanisms. The authors used a liquid chromatography-mass spectrometry metabolomics approach to analyze the metabolic changes induced by hawthorn extract, seeking to understand its therapeutic effects on blood stasis.
A Metabolic Oasis: Hawthorn's Impact on Blood Stasis
The study, like a camel caravan traversing the desert of metabolic research, investigated the effects of hawthorn extract on blood stasis. The findings, like hidden oases in the vast desert of metabolic pathways, revealed significant therapeutic effects of the n-butanol and ethyl acetate fractions of hawthorn extract on blood stasis model rats. These fractions demonstrated improvement in hemorheology and fibrinogen levels, suggesting a potential role in reducing blood viscosity and promoting blood flow. The metabolomics analysis further revealed that these fractions reversed imbalanced biomarkers in plasma and urine, indicating a potential impact on multiple metabolic pathways.
Navigating the Desert of Cardiovascular Health: The Potential of Hawthorn
This study, like a compass guiding travelers through the desert of cardiovascular health, highlights the potential therapeutic effects of hawthorn extract, particularly the n-butanol and ethyl acetate fractions. The study's findings suggest that these fractions may offer benefits in addressing blood stasis, a condition often associated with cardiovascular disease. This research encourages further investigation into the mechanisms of action and potential clinical applications of hawthorn extract in promoting cardiovascular health.
Dr.Camel's Conclusion
This study, like a shimmering mirage in the desert, reveals the potential therapeutic effects of hawthorn extract on blood stasis. The study's findings suggest that specific fractions of hawthorn extract may offer benefits in addressing this condition, prompting further research into its mechanisms and potential clinical applications. As researchers continue to explore the vast desert of natural remedies, we strive to uncover new and effective therapies for promoting health and well-being.
Date :
- Date Completed 2022-02-15
- Date Revised 2022-02-15
Further Info :
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