Paper Details 
Original Abstract of the Article :
Anaplastic thyroid cancer (ATC) is one of the most fatal human malignancies. Ursi Fel (UF) is the bile of a brown bear that has been traditionally used for heat clearance and toxin relief in Korean and Chinese medicines. In this study, we determined the anticancer effects of a UF extract and its act...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8434085/

データ提供:米国国立医学図書館(NLM)

Anticancer Effects of Ursi Fel Extract in Anaplastic Thyroid Cancer

This study investigates the anticancer effects of Ursi Fel (UF) extract and its active compound, ursodeoxycholic acid (UDCA), in FRO human anaplastic thyroid cancer (ATC) cells. Anaplastic thyroid cancer is an aggressive and often fatal malignancy, highlighting the need for new and effective treatment options. The study examined the effects of UF extract and UDCA on the growth and survival of FRO cells, assessing cell viability, apoptosis, and the expression of key proteins involved in apoptosis and angiogenesis. The study's findings demonstrate that UF extract and UDCA exhibit significant anticancer properties, inhibiting cell growth, inducing apoptosis, and regulating the Akt/mTOR signaling pathway, suggesting potential therapeutic applications for ATC treatment.

Ursi Fel Extract: A Potential Weapon Against Thyroid Cancer

The study's findings provide a promising lead in the search for effective therapies for anaplastic thyroid cancer. The demonstration of anticancer properties of UF extract and UDCA suggests potential therapeutic benefits for ATC patients. Further research is needed to investigate the clinical application of these compounds in treating ATC.

Exploring New Avenues for Thyroid Cancer Treatment

This research highlights the importance of exploring traditional medicine and natural compounds for potential anticancer therapies. The study's findings encourage further research into the mechanisms of action of UF extract and UDCA, paving the way for the development of new and effective treatments for anaplastic thyroid cancer. The research emphasizes the need for a holistic approach to cancer treatment, considering both conventional therapies and traditional medicine.

Dr. Camel's Conclusion

Imagine a vast desert, where ancient traditions and modern science converge. Ursi Fel extract, like a hidden oasis of medicinal potential, emerges from the depths of traditional knowledge. This study reveals its promising anticancer properties, offering hope for a future where traditional and modern medicine can collaborate to conquer the challenges of anaplastic thyroid cancer. The journey continues, and Dr. Camel is eagerly awaiting further discoveries in this exciting realm.

Date :
  1. Date Completed 2021-11-09
  2. Date Revised 2021-11-09
Further Info :

Pubmed ID

34500742

DOI: Digital Object Identifier

PMC8434085

Related Literature

SNS
PICO Info
in preparation
Languages

English

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