Paper Details

  1. Home
  2. Paper Details

Vitamin D oral intermittent treatment (DO IT) study, a randomized clinical trial with individual loading regimen.

Author: ArnetIsabelle, HersbergerKurt E, RothenJean-Pierre, RutishauserJonas, WalterPhilipp N

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study compared different ways to take vitamin D supplements to treat vitamin D deficiency. It found that a personalized, higher initial dose (loading regimen) taken weekly was more effective in raising vitamin D levels to a healthy range compared to taking a lower dose monthly. The loading regimen resulted in all participants reaching sufficient vitamin D levels and a higher percentage reaching higher levels (greater than 75 nmol/l). The study also found no side effects and that patients preferred taking capsules over a liquid form.
Paper Details　
Original Abstract of the Article :
Comparison of several regimens of oral vitamin D including an individually calculated loading regimen with the aim of achieving serum values > 75 nmol/l. Interventional, randomized, 3-arm study in vitamin D-deficient outpatients. Participants were allocated to supplementatio...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455639/

データ提供：米国国立医学図書館（NLM）

Vitamin D: A Tailored Approach to Achieving Optimal Levels

This study explores the optimal ways to administer vitamin D to achieve sufficient serum levels. It's like a quest to find the perfect balance in a desert ecosystem, carefully adjusting the amount of sunlight and water to ensure the well-being of its inhabitants. This research explores different approaches to vitamin D supplementation, comparing a fixed monthly dose to an individualized loading regimen. It's like comparing different irrigation methods, each with its own strengths and weaknesses.

A Personalized Approach: Loading Regimen for Vitamin D

The findings demonstrate that an individualized loading regimen, calculated based on baseline vitamin D levels and body weight, was more effective in achieving sufficient vitamin D levels than a fixed monthly dose. This personalized approach is like tailoring clothing to a specific individual, ensuring the best fit and comfort. It's a reminder that one-size-fits-all approaches may not always be the most effective, especially when it comes to individual health needs.

Sunshine for Your Bones and Beyond: Vitamin D's Importance

This research highlights the importance of achieving sufficient vitamin D levels for optimal health. It's like ensuring that a desert oasis has enough water to sustain life. Vitamin D is essential for strong bones, immune function, and even mood regulation. This study provides valuable information for healthcare providers and individuals seeking to optimize their vitamin D levels through personalized supplementation strategies.

Dr.Camel's Conclusion

This study emphasizes the importance of personalized approaches to vitamin D supplementation. It's like finding the perfect balance between the sun and the sand, ensuring optimal health and well-being. By understanding individual needs and tailoring treatment strategies accordingly, we can effectively optimize vitamin D levels and reap its numerous health benefits.

Date :
  1. Date Completed 2021-12-30
  2. Date Revised 2023-11-07
Further Info :

Pubmed ID

34548526

DOI: Digital Object Identifier

PMC8455639

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.