Paper Details 
Original Abstract of the Article :
Herein, we demonstrated the development and characterization of a dry powder inhaler (DPI) formulation of edoxaban (EDX); and investigated the in-vitro anticoagulation effect for the management of pulmonary or cerebral coagulopathy associated with COVID-19 infection. The formulations were prepared b...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463814/

データ提供:米国国立医学図書館(NLM)

Inhaled Edoxaban for COVID-19 Coagulopathy: A New Frontier in Respiratory Treatment

The field of respiratory medicine, like a vast and ever-changing desert landscape, is constantly seeking new and innovative approaches to treat respiratory illnesses. This study, like a team of researchers venturing into the uncharted territory of inhaled drug delivery, explores the development and characterization of a dry powder inhaler (DPI) formulation of edoxaban (EDX) for the management of pulmonary or cerebral coagulopathy associated with COVID-19 infection. The researchers, like skilled engineers, designed and characterized a novel DPI formulation of EDX, carefully optimizing its aerosolization properties and in vitro anticoagulation effects. Their findings suggest that this inhaled formulation could be a potential and effective treatment for managing the coagulopathy associated with COVID-19 infection, offering a new approach to combat this challenging disease.

A Breath of Fresh Air for COVID-19 Patients: Inhaled Edoxaban

The study's findings, like a refreshing oasis in the desert of COVID-19 treatment, highlight the potential of inhaled EDX to combat the coagulopathy associated with this disease. The researchers demonstrated that their novel DPI formulation of EDX exhibited promising in vitro anticoagulation effects, suggesting that this approach could be a valuable tool for managing the blood clotting complications associated with COVID-19.

A New Hope for Respiratory Health: The Power of Inhalation

This research, like a new desert oasis, offers hope for individuals struggling with the respiratory complications of COVID-19. The study's findings suggest that inhaled EDX could be a promising treatment option, offering a non-invasive and convenient way to combat the coagulopathy associated with this disease. It's like discovering a new source of water in the desert, offering a lifeline for those who need it most.

Dr. Camel's Conclusion

This study, like a caravan of innovation, highlights the potential of inhaled edoxaban as a new frontier in respiratory treatment. The researchers' findings offer a promising approach to managing the coagulopathy associated with COVID-19 infection, offering a potential solution for a challenging medical problem. Remember, just as a desert traveler relies on their camel for strength and resilience, we can rely on innovation and research to find solutions to the challenges we face in the world of medicine.

Date :
  1. Date Completed 2021-10-12
  2. Date Revised 2022-12-21
Further Info :

Pubmed ID

34560207

DOI: Digital Object Identifier

PMC8463814

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Languages

English

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