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The Cost-Effectiveness of Three Prevention Strategies in Alzheimer's Disease: Results from the Multidomain Alzheimer Preventive Trial (MAPT).

Author: AndrieuS, CantetC, CarriéI, ColeyN, CostaN, DerumeauxH, GuyonnetS, MolinierL, MouniéM, PagèsA, RappT

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

A cost-effectiveness analysis of three preventive strategies for Alzheimer's disease (AD) compared to a placebo using data from the Multidomain Alzheimer Preventive Trial (MAPT) study found that multidomain intervention (MI) combined with polyunsaturated fatty acids (PFA) and MI alone were cost-effective strategies, with an incremental cost-effectiveness ratio (ICER) below the willingness-to-pay threshold of €50,000 per improved cognitive Z-score point. PFA alone was not cost-effective.
Paper Details　
Original Abstract of the Article :
BACKGROUND: To date, no curative treatment is available for Alzheimer's disease (AD). Therefore, efforts should focus on prevention strategies to improve the efficiency of healthcare systems. OBJECTIVE: Our aim was to assess the cost-effectiveness of three preventive strategies for AD compared to a...See full text at original site
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引用元：
https://doi.org/10.14283/jpad.2021.47

データ提供：米国国立医学図書館（NLM）

Cost-Effectiveness of Alzheimer's Prevention: A Camel's Perspective on Investing in a Healthy Mind

Alzheimer's disease, like a relentless desert sandstorm, gradually erodes our cognitive abilities. This research examines the cost-effectiveness of three prevention strategies for Alzheimer's disease: multidomain intervention (MI), polyunsaturated fatty acids (PFA), and a combination of MI and PFA. The authors analyzed data from the Multidomain Alzheimer Preventive Trial (MAPT) to assess the cost-effectiveness of these interventions compared to a placebo. Their findings suggest that MI combined with PFA and MI alone are cost-effective strategies, while PFA alone is less cost-effective. This research provides valuable information for policymakers and healthcare providers in making informed decisions about Alzheimer's prevention.

A Camel's Perspective on Investing in a Healthy Mind: Cost-Effectiveness of Alzheimer's Prevention

This research highlights the importance of investing in Alzheimer's prevention, demonstrating the cost-effectiveness of certain interventions. The study's findings suggest that multidomain intervention (MI) combined with polyunsaturated fatty acids (PFA) and MI alone are cost-effective strategies for preventing Alzheimer's disease.

A Camel's Perspective on Investing in a Healthy Mind: Protecting Our Cognitive Oasis

Alzheimer's disease is a complex and devastating condition, but research suggests that there are steps we can take to reduce our risk. This research emphasizes the importance of adopting a healthy lifestyle, including a balanced diet, regular exercise, and cognitive stimulation, to protect our cognitive oasis.

Dr.Camel's Conclusion

This research offers a compelling argument for investing in Alzheimer's prevention, demonstrating the cost-effectiveness of certain interventions. The findings suggest that multidomain intervention (MI) combined with polyunsaturated fatty acids (PFA) and MI alone are cost-effective strategies. By understanding the potential benefits of these interventions, policymakers and healthcare providers can make informed decisions to prioritize Alzheimer's prevention and protect our cognitive well-being.

Date :
  1. Date Completed 2021-11-01
  2. Date Revised 2022-01-23
Further Info :

Pubmed ID

34585216

DOI: Digital Object Identifier

10.14283/jpad.2021.47

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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