[Pharmacokinetics and clinical evaluation of cefotiam in pediatric surgery].

Author: HashimotoT, HayashiS, KamiyaY, MurataY, TsurugaN, YuraJ

Paper Details 
Original Abstract of the Article :
Pharmacokinetics and clinical studies on cefotiam (CTM) in pediatric surgery were performed and the results obtained are summarized below. In neonates without congenital heart disease (CHD), serum levels of CTM were rapidly increased following injection of CTM (20 mg/kg, one shot intravenous adminis...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/3467089

データ提供:米国国立医学図書館(NLM)

Cefotiam's Journey Through the Body: A Pediatric Perspective

In the vast desert of pediatric surgery, finding the right antibiotic for a young camel is a challenging quest. This study focuses on the pharmacokinetics of cefotiam, a powerful antibiotic, in pediatric surgery. The researchers used a method like tracking the movement of a caravan through the desert, analyzing blood and urine samples. Their findings reveal that cefotiam travels quickly through the body of healthy newborns, much like a swift camel traversing the dunes. However, in newborns with heart defects, the journey is slower, like a camel struggling through a sandstorm. This study sheds light on the importance of customizing antibiotic treatment based on individual factors like heart health, as different camels may need different strategies to navigate the desert.

Cefotiam's Effectiveness: A Promising Oasis in Pediatric Surgery

The study found that cefotiam was effective in preventing postoperative infections in most cases, like a well-equipped caravan avoiding pitfalls in the desert. The study also found that cefotiam was safe and well-tolerated, like a reliable oasis providing much-needed refreshment for weary travelers. However, two patients still developed wound infections, demonstrating that no oasis is foolproof. This emphasizes the importance of ongoing vigilance and a multi-faceted approach to fighting infections.

The Camel's Perspective: A Tale of Antibiotic Management

This study reminds us that each patient is like a camel with its own unique journey. The researchers highlight the importance of adjusting treatment plans based on individual factors to ensure optimal results, much like guiding a caravan through a diverse and challenging desert landscape. Understanding these individual differences is crucial for successful antibiotic management, ensuring that every camel reaches its destination safe and sound.

Dr. Camel's Conclusion

This study provides invaluable insights into the behavior of cefotiam in pediatric surgery, like a well-mapped oasis in the vast desert of medical knowledge. While the study demonstrates cefotiam's effectiveness, it also underscores the importance of individualized treatment based on each patient's unique characteristics, just like tailoring a caravan's route to suit the specific challenges of the desert.

Date :
  1. Date Completed 1987-02-17
  2. Date Revised 2016-11-16
Further Info :

Pubmed ID

3467089

DOI: Digital Object Identifier

3467089

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SNS
PICO Info
in preparation
Languages

Japanese

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