Immunogenic Cell Death and Immunomodulatory Effects of Cabozantinib.

Author: Di FilippoAlessandra, NapoletanoChiara, NutiMarianna, PaceAngelica, Rahimi KoshkakiHassan, RughettiAurelia, ScirocchiFabio, ZizzariIlaria Grazia

Paper Details 
Original Abstract of the Article :
Cabozantinib (XL-184) is a multitarget tyrosine kinase inhibitor (TKI) targeting receptor tyrosine kinases (RTKs) involved in oncogenesis and angiogenesis. It is currently the standard therapy for medullary thyroid cancer (MTC), metastatic renal cell carcinoma (mRCC), and hepatocellular carcinoma (H...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564482/

データ提供:米国国立医学図書館(NLM)

Cabozantinib: A Multifaceted Weapon Against Cancer

Cabozantinib, a targeted therapy used for various cancers, shows promising potential not only as a cancer killer but also as an immune system booster. Researchers are investigating the immunostimulatory effects of Cabozantinib, particularly its ability to induce immunogenic cell death in prostate cancer cells. They found that Cabozantinib can trigger a cascade of events that lead to the death of cancer cells while simultaneously activating the immune system to target and destroy remaining cancer cells. This exciting discovery could lead to new and more effective cancer treatments.

Cabozantinib's Double-Edged Sword

Cabozantinib's dual ability to kill cancer cells and activate the immune system is like a double-edged sword, striking down cancer cells while simultaneously empowering the immune system to fight back. This multifaceted approach holds promise for the development of more effective cancer treatments.

Harnessing the Power of the Immune System

Cabozantinib's ability to stimulate the immune system offers a new avenue for cancer treatment. It is like adding fuel to the fire of the immune system, empowering it to more effectively target and eliminate cancer cells. This approach could lead to more durable responses and potentially even cure some cancers.

Dr.Camel's Conclusion

Cabozantinib is a powerful drug that can not only kill cancer cells but also boost the immune system. This is a promising development that could lead to better cancer treatments. It's like finding a hidden oasis in the desert - a new and effective weapon in the fight against cancer.

Date :
  1. Date Completed n.d.
  2. Date Revised 2021-11-10
Further Info :

Pubmed ID

34745989

DOI: Digital Object Identifier

PMC8564482

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.