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Managing Recurrent Clozapine-Induced Constipation in a Patient with Resistant Schizophrenia.

Author: BoukakiouReda, TomulescuSilviu, UittenhoveKim

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.

Overview

Clozapine, an effective antipsychotic for treatment-resistant schizophrenia, can cause serious side effects, particularly constipation and ileus. This case report describes a patient with repeated episodes of ileus while on clozapine and outlines the successful management strategy involving medication adjustments, linaclotide administration, and surgical intervention.
Paper Details　
Original Abstract of the Article :
Clozapine is an effective antipsychotic for the treatment of resistant schizophrenia. However, clozapine can lead to serious side effects. One of the most common side effects is constipation and in rare cases ileus, which is associated with a considerable case fatality rate. Our patient exhibited re...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8592763/

データ提供：米国国立医学図書館（NLM）

Clozapine-Induced Constipation: A Desert of Digestive Distress

This research explores the challenges of managing clozapine-induced constipation, a common side effect of this effective antipsychotic medication. Researchers are like desert explorers, seeking ways to alleviate the discomfort and potential complications associated with this side effect. This case report details a patient with resistant schizophrenia who experienced repeated episodes of ileus while on clozapine therapy.

Navigating the Sand Dunes of Constipation

The study's findings highlight the importance of a multi-faceted approach to managing clozapine-induced constipation. This case report illustrates the effectiveness of a tailored treatment strategy involving medication adjustments, the addition of non-conventional laxatives, and surgical intervention when necessary. It's like discovering a hidden oasis in the desert, providing relief from the discomfort and potential complications of this side effect.

Finding Relief in the Desert of Digestive Distress

This study underscores the importance of close monitoring and proactive management of clozapine-induced constipation, especially in patients with a history of severe complications. It emphasizes the need for collaboration between patients and healthcare providers to identify and address potential issues early on.

Dr.Camel's Conclusion

This case report offers a valuable lesson in the management of clozapine-induced constipation. The study demonstrates the importance of a tailored and multidisciplinary approach to alleviate this common and potentially serious side effect. Just as a camel navigates a challenging desert landscape, healthcare providers must be prepared to adjust treatment strategies to meet the unique needs of each patient.

Date :
  1. Date Completed n.d.
  2. Date Revised 2021-11-19
Further Info :

Pubmed ID

34790422

DOI: Digital Object Identifier

PMC8592763

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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