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Effects of Astragalus Extract Mixture HT042 on Circulating IGF-1 Level and Growth Hormone Axis in Rats.

Author: ChoWon-Young, KimByung-Hak, KimHocheol, KimYoung-Sik, LeeDonghun, LeeSung-Hyun

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

<i>Astragalus</i> extract mixture HT042 increased circulatory IGF-1 levels, stimulated GH secretion through modulation of GHRH-R and GHS-R in the pituitary, and promoted bone formation in cartilage. The growth-promoting effect of HT042 was mediated by GH/IGF-1 pathways, suggesting its potential for promoting children's height growth.
Paper Details　
Original Abstract of the Article :
<i>Astragalus</i> extract mixture HT042 is a standardized functional food granted by the Korean FDA for promoting "Children's Height Growth". In this study, we determined whether HT042 affects circulatory Insulin-like growth factor-1 (IGF-1) after administration and investigated whether Growth horm...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8622163/

データ提供：米国国立医学図書館（NLM）

Astragalus Extract HT042: A Camel's Journey into Height Growth

This study, like a camel traversing a vast desert of research on growth and development, investigates the effects of Astragalus extract mixture HT042 on circulating IGF-1 levels and the growth hormone axis in rats. The authors conducted a series of experiments to determine the potential growth-promoting effects of HT042, a standardized functional food designed to promote children's height growth. Their findings, like a blossoming oasis in the arid landscape of growth research, reveal that HT042 can modulate the activity of the growth hormone axis, potentially contributing to an increase in serum IGF-1.

The Growth Hormone Axis: A Desert Oasis of Height

This study provides valuable insights into the potential of HT042 in promoting growth, particularly in children. The authors discovered that HT042 modulates the activity of the growth hormone axis, a complex system responsible for regulating growth and development. This modulation may contribute to increased IGF-1 levels, a key hormone involved in growth processes. These findings hold promise for the development of natural remedies to support healthy growth and development.

A Camel's Guide to Growth: Seeking a Height Advantage

This study suggests that HT042, a standardized functional food, may play a role in promoting growth and development. While further research is needed to confirm its efficacy in humans, the study's findings offer hope for individuals seeking to enhance their growth potential. However, it is crucial to consult with healthcare providers for personalized advice and guidance.

Dr.Camel's Conclusion

This study unveils a promising avenue for enhancing growth potential, highlighting the potential of natural remedies in promoting healthy development. The researchers, like skilled camel breeders, have explored the complex pathways of growth, revealing the potential of Astragalus extract HT042 in modulating the growth hormone axis. This research journey, like a camel's trek across the desert, leads us towards a deeper understanding of growth and development, potentially paving the way for innovative interventions to support healthy growth in children.
Date :
  1. Date Completed n.d.
  2. Date Revised 2021-11-30
Further Info :

Pubmed ID

34828688

DOI: Digital Object Identifier

PMC8622163

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Languages

English

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