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Lipid Nanocarriers for Hyperproliferative Skin Diseases.

Author: CanoAmanda, ChorilliMarlus, Dos SantosFernanda K, GremiãoMaria P D, KarczewskiJacek, Sanchez-LopezElena, SoutoEliana B, StaszewskiRafał, ZielińskaAleksandra, de SouzaAna L R

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Hyperproliferative skin diseases (HSD) are a group of skin conditions requiring anti-proliferative therapies. Many anti-proliferative agents, including 5-fluorouracil, imiquimod, and methotrexate, have low aqueous solubility, limiting their skin permeation. This manuscript discusses the advantages of using lipid nanoparticles and liposomes as drug delivery systems for HSD treatment. These nanocarriers offer improved drug delivery, enhanced efficacy, and reduced side effects compared to conventional topical therapies.
Paper Details　
Original Abstract of the Article :
Hyperproliferative skin diseases (HSD) are a group of diseases that include cancers, pre-cancerous lesions and diseases of unknown etiology that present different skin manifestations in terms of the degree and distribution of the injuries. Anti-proliferative agents used to treat these diseases are s...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615830/

データ提供：米国国立医学図書館（NLM）

Lipid Nanocarriers: A Delivery System for Hyperproliferative Skin Diseases

The skin is our body's largest organ, constantly working to protect us from the world. When its cells begin to proliferate excessively, it can lead to a range of skin conditions, some of which are benign, while others can be more serious. This research explores the potential of lipid nanocarriers as a delivery system for anti-proliferative agents, aiming to enhance the effectiveness of topical treatments while minimizing side effects. These nanocarriers act like miniature transporters, encapsulating drugs and delivering them directly to the target site, improving absorption and reducing potential complications.

Targeted Therapy for Skin Conditions

The study highlights the advantages of using lipid nanoparticles and liposomes for treating hyperproliferative skin diseases. These nanocarriers can encapsulate various anti-proliferative agents, enhancing their efficacy and bioavailability. This targeted approach could potentially improve treatment outcomes and reduce the need for systemic medications, thereby minimizing unwanted side effects.

A Targeted Approach for Skin Health

The use of lipid nanocarriers in the treatment of hyperproliferative skin diseases represents a promising advancement. These intelligent carriers act like miniature camels, traversing the skin's landscape to deliver their precious cargo of therapeutic agents directly to the target cells. By optimizing drug delivery, we can potentially achieve better results and reduce the burden of side effects for patients. Always consult with a dermatologist for personalized advice and treatment recommendations for any skin conditions.

Dr.Camel's Conclusion

This research sheds light on the exciting potential of lipid nanocarriers in the treatment of hyperproliferative skin diseases. It's a reminder that innovative technologies are continually emerging, offering new hope and solutions for patients with various skin conditions. Remember, healthy skin is essential for our overall well-being, so take care of it and seek professional guidance when needed.

Date :
  1. Date Completed n.d.
  2. Date Revised 2021-11-29
Further Info :

Pubmed ID

34830774

DOI: Digital Object Identifier

PMC8615830

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Languages

English

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