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Effects of long-term testosterone treatment on cardiovascular outcomes in men with hypogonadism: Rationale and design of the TRAVERSE study.

Author: , BasariaShehzad, BauerDouglas C, BhasinShalender, BodenWilliam E, CunninghamGlenn R, DaveyDeborah, DubcencoElena, FukumotoSandra, GarciaMichelle, GrangerChristopher B, KalahastiVidyasagar, KheraMohit, LincoffA Michael, MillerMichael G, MitchellLisa M, NissenSteven E, O'LearyMichael P, PencinaKarol M, SnyderPeter J, ThompsonIan M, TravisonThomas G, WolskiKathy

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Testosterone may have some benefits for the cardiovascular system, but it may also increase the risk of heart problems. There haven't been any large studies to look at the long-term effects of testosterone treatment.
Paper Details　
Original Abstract of the Article :
Testosterone exerts some effects on the cardiovascular system that could be considered beneficial; some other effects may potentially increase the risk of cardiovascular (CV) events. Neither the long-term efficacy nor safety of testosterone treatment has been studied in an adequately-powered randomi...See full text at original site
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引用元：
https://doi.org/10.1016/j.ahj.2021.11.016

データ提供：米国国立医学図書館（NLM）

Testosterone Therapy: A Balancing Act in Hypogonadism

This study delves into the complex interplay of testosterone and cardiovascular health in men with hypogonadism. Imagine a desert oasis where testosterone is both a source of life-giving water and a potential sandstorm. The authors are embarking on a clinical trial (TRAVERSE) to determine the long-term effects of testosterone therapy on cardiovascular outcomes. They are exploring the potential benefits and risks, aiming to provide clinicians with a more comprehensive understanding of this controversial treatment.

Navigating the Uncertainties of Testosterone Therapy

The TRAVERSE study seeks to shed light on the long-term effects of testosterone therapy in men with hypogonadism. It is a crucial step towards addressing the uncertainties surrounding this treatment and making informed decisions about its use. The results of this study are eagerly anticipated by both clinicians and patients.

Balancing the Oasis and the Sandstorm

Testosterone therapy can be a double-edged sword. It can improve certain aspects of cardiovascular health, but it may also increase the risk of adverse events. The TRAVERSE study aims to carefully navigate this complex landscape and provide valuable insights into the long-term effects of testosterone therapy. This research will help clinicians and patients make informed decisions about testosterone therapy, ensuring that the benefits outweigh the risks.

Dr.Camel's Conclusion

This research is a testament to the commitment of scientists to explore complex medical questions. By unraveling the mysteries of testosterone therapy and its impact on cardiovascular health, this study could revolutionize the way we approach the management of hypogonadism. It's a reminder that even in the ever-changing sands of medical knowledge, there's always room for new discoveries and a quest for better outcomes.

Date :
  1. Date Completed 2022-04-07
  2. Date Revised 2022-04-07
Further Info :

Pubmed ID

34871580

DOI: Digital Object Identifier

10.1016/j.ahj.2021.11.016

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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