Intensive drug therapy versus standard drug therapy for symptomatic intestinal Crohn's disease strictures (STRIDENT): an open-label, single-centre, randomised controlled trial.

Author: BellSally J, ChristensenBritt, ConnellWilliam C, De CruzPeter, DingNik S, HamiltonAmy L, HoltBronte A, KammMichael A, LustMark, MillerAshley M, MooreGregory T, RongYuwei J, RossAlyson L, SchulbergJulien D, SheltonEdward, SutherlandTom R, VogrinSara, WrightEmily K

Paper Details 
Original Abstract of the Article :
Strictures are the most common structural complication of Crohn's disease. Surgery and endoscopic balloon dilation are the main treatments; drug therapy has been considered contraindicated. Given that most strictures have an inflammatory component, we aimed to find out whether strictures are respons...See full text at original site
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引用元:
https://doi.org/10.1016/S2468-1253(21)00393-9

データ提供:米国国立医学図書館(NLM)

Intensive Drug Therapy: Can We Tame the Wild Crohn's Disease?

Crohn's disease, like a tempestuous desert wind, can be a real challenge for those who suffer from it. This study, employing an [open-label, single-centre, randomised controlled trial], set out to explore whether [intensive drug therapy] can effectively manage [symptomatic intestinal Crohn's disease strictures]. The authors discovered that [intensive drug therapy] may offer a viable alternative to [surgery and endoscopic balloon dilation], potentially mitigating the need for invasive procedures.

A New Approach to Managing Crohn's Disease

The study indicates that [intensive drug therapy] may be a valuable strategy for managing [symptomatic intestinal Crohn's disease strictures]. This research, like a camel caravan finding a fertile oasis in the desert, offers a new perspective on how we might approach this challenging disease.

Living with Crohn's Disease: A Balanced Diet

While this research offers hope for managing [symptomatic intestinal Crohn's disease strictures], it is essential to remember that there is no one-size-fits-all solution for this complex disease. A healthy lifestyle, including a balanced diet and regular exercise, can play a vital role in managing symptoms and improving overall well-being.

Dr.Camel's Conclusion

This study, like a camel caravan braving a sandstorm, is a testament to the ongoing efforts to combat Crohn's disease. While [intensive drug therapy] may offer a promising alternative, it's crucial to work closely with your doctor to create a personalized treatment plan. Ultimately, managing Crohn's disease is like navigating a shifting desert landscape – it requires patience, perseverance, and a willingness to adapt.

Date :
  1. Date Completed 2022-04-20
  2. Date Revised 2022-04-20
Further Info :

Pubmed ID

34890567

DOI: Digital Object Identifier

10.1016/S2468-1253(21)00393-9

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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