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The effects of raloxifene on endothelial function and Inflammation in Postmenopausal women: A Meta-analysis of randomized controlled trials.

Author: HuangJiazhen, KangFuli, ZouQi

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Raloxifene is a medication used to treat osteoporosis in postmenopausal women. This systematic review and meta-analysis evaluated the effect of raloxifene on endothelial function and inflammation in postmenopausal women.
Paper Details　
Original Abstract of the Article :
Raloxifene treatment has been reported to be associated with cardiovascular benefits if prescribed to women during the postmenopausal period. However, a final conclusion regarding this hypothesis has not yet been achieved. We conducted a systematic review and meta-analysis to evaluate the effect of ...See full text at original site
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引用元：
https://doi.org/10.1016/j.exger.2021.111682

データ提供：米国国立医学図書館（NLM）

Raloxifene and Postmenopausal Women: A Journey Through the Desert of Estrogen Deficiency

Menopause, a natural transition in a woman's life, can sometimes be accompanied by a cascade of physiological changes. Raloxifene, a selective estrogen receptor modulator (SERM), has been investigated for its potential benefits in managing these changes, particularly in the realm of cardiovascular health. This research delves into the effects of raloxifene on endothelial function and inflammation in postmenopausal women, seeking to shed light on its potential cardiovascular benefits.

Exploring the Oasis of Cardiovascular Health

The study examines the impact of raloxifene on endothelial function and inflammation, key factors in cardiovascular health. The authors conducted a systematic review and meta-analysis of randomized controlled trials, finding that raloxifene may have a positive impact on endothelial function, but the evidence regarding its effects on inflammation is inconclusive. Further research is needed to fully understand the cardiovascular benefits of raloxifene in postmenopausal women.

Navigating the Crossroads of Menopause and Cardiovascular Health

Menopause, a natural transition that marks the end of a woman's reproductive years, can sometimes bring about changes in cardiovascular health. Understanding the potential benefits and risks of medications like raloxifene is crucial for making informed choices about managing these changes. By working closely with your healthcare provider, you can navigate the complex landscape of menopause and cardiovascular health with greater confidence and well-being.

Dr. Camel's Conclusion

This research reminds us that the journey through menopause can be complex, with potential challenges to cardiovascular health. Raloxifene, a potential oasis in the desert of estrogen deficiency, may offer certain cardiovascular benefits, but further research is needed to solidify its role in managing postmenopausal health. By staying informed about the latest research and collaborating with your healthcare provider, you can navigate this transition with greater knowledge and assurance.

Date :
  1. Date Completed 2022-03-03
  2. Date Revised 2022-03-03
Further Info :

Pubmed ID

34973344

DOI: Digital Object Identifier

10.1016/j.exger.2021.111682

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in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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