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[Comparative study of the treatment of simple urinary infection with a single dose of norfloxacin versus cotrimoxazole].

Author: BilleJ, DarioliR, GlauserM P, de VeveyP

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study compared the effectiveness of a single dose of norfloxacin and cotrimoxazole in treating 53 women with uncomplicated urinary tract infections. Both antibiotics had similar success rates (85%) after one week. Both treatments were well-tolerated, with only minor side effects. Most treatment failures were due to gram-positive bacteria. The study concludes that single-dose therapy may be a viable option for treating urinary tract infections caused by gram-positive bacteria.
Paper Details　
Original Abstract of the Article :
53 women with acute, uncomplicated urinary tract infection proven clinically and bacteriologically were treated, after double-blind randomisation, with a single dose of norfloxacin (1200 mg) or a single dose of cotrimoxazole (480/2400 mg). Follow-up one week after treatment showed a comparable succe...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/3497450

データ提供：米国国立医学図書館（NLM）

Single-Dose Therapy for Urinary Tract Infections: A Comparative Study

Urinary tract infections are a common ailment that can cause significant discomfort. This research compares the effectiveness of two single-dose antibiotic treatments, norfloxacin and cotrimoxazole, for uncomplicated urinary tract infections. The study found that both treatments had similar success rates, but norfloxacin was slightly more effective against gram-positive bacteria. The researchers suggest that single-dose therapy for infections caused by gram-positive bacteria may need to be reconsidered.

Evaluating Treatment Options

This research provides valuable information for clinicians and patients considering treatment options for uncomplicated urinary tract infections. The findings suggest that both norfloxacin and cotrimoxazole can be effective single-dose treatments, but the choice of antibiotic may depend on the specific bacteria causing the infection. This study highlights the importance of carefully evaluating treatment options and selecting the most appropriate therapy based on individual factors.

Taking Care of Your Urinary Tract

Urinary tract infections can be uncomfortable and inconvenient. This study reminds us that there are effective treatments available. If you experience symptoms of a urinary tract infection, it's important to consult with your doctor to discuss the best treatment options for you. Remember, early diagnosis and treatment are key to preventing complications and ensuring a speedy recovery.

Dr.Camel's Conclusion

This study emphasizes the importance of evidence-based decision-making when choosing treatments for urinary tract infections. Just as a desert nomad carefully assesses water sources, we need to carefully evaluate the options available to us for optimal health. This research provides insights into the effectiveness of different therapies, helping us to navigate the complexities of infection management.

Date :
  1. Date Completed 1987-08-31
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

3497450

DOI: Digital Object Identifier

3497450

Related Literature

Article Analysis
・Effective treatment of urinary tract infections
SNS
PICO Info
in preparation
Languages

French

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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