[Synephrine in dietary supplements and specialized foodstuffs: biological activity, safety and methods of analysis].

Author: EllerK I, MusatovA V, PerovaI B, TymolskayaE V

Paper Details 
Original Abstract of the Article :
Synephrine is a natural protoalkaloid of the bitter orange Citrus aurantium L., it has structural similarity to ephedrine and adrenaline. Synephrine in the form of bitter orange extract is widely used as an ingredient of dietary supplements (DS) and specialized foodstuffs (SF) intended for weight lo...See full text at original site
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引用元:
https://doi.org/10.33029/0042-8833-2021-90-6-101-113

データ提供:米国国立医学図書館(NLM)

Synephrine in Dietary Supplements and Specialized Foodstuffs

This review explores the biological activity, safety, and analytical methods for synephrine, a natural compound found in bitter orange (Citrus aurantium L.). Synephrine is often used as an ingredient in dietary supplements (DS) and specialized foodstuffs (SF) marketed for weight loss and fitness enhancement. This review examines the potential benefits and risks associated with synephrine consumption, along with regulatory considerations and analytical approaches for its detection.

Synephrine's Adrenergic Effects and Potential Risks

The review highlights that synephrine's primary biological activity is due to its adrenergic effects, stimulating the release of adrenaline and other hormones, leading to increased thermogenesis and lipolysis, promoting fat burning. However, it also underscores the potential for cardiovascular side effects, especially when combined with caffeine and physical activity. The review emphasizes the need for careful regulation of synephrine consumption, as insufficient safety data exists, particularly for individuals with underlying cardiovascular conditions. It's like walking through a desert landscape, where the allure of a shimmering oasis may hide unexpected dangers.

Regulation and Analysis of Synephrine in Dietary Supplements

This review underscores the importance of regulating synephrine content in dietary supplements and specialized foodstuffs. It highlights the need for accurate analytical methods to monitor synephrine levels and prevent potential adulteration with synthetic synephrine or its isomers. The review emphasizes the importance of consumer awareness regarding synephrine's potential risks and the need for appropriate regulatory measures to ensure product safety. It's like navigating a desert with a compass, ensuring we are aware of our surroundings and have the necessary tools to stay safe and on track.

Dr.Camel's Conclusion

This review emphasizes the importance of understanding the biological effects and potential risks associated with synephrine consumption. It's like traversing a desert where the allure of a quick fix might lead to unexpected consequences. This research highlights the importance of careful regulation, accurate analysis, and consumer awareness to ensure the safe and responsible use of synephrine in dietary supplements and specialized foodstuffs.

Date :
  1. Date Completed 2022-02-22
  2. Date Revised 2022-02-22
Further Info :

Pubmed ID

35032130

DOI: Digital Object Identifier

10.33029/0042-8833-2021-90-6-101-113

SNS
PICO Info
in preparation
Languages

Russian

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