Carbapenemase-producing Enterobacterales infections: recent advances in diagnosis and treatment.

Author: ChenHsien-Meng, HiiIng-Moi, HsuehPo-Ren, LeeYu-Lin

Paper Details 
Original Abstract of the Article :
Increasing carbapenem resistance in Enterobacterales poses a threat to public health. In recent decades, this increase in carbapenem resistance has been caused by the global dissemination of carbapenemase-producing Enterobacterales (CPE). Carbapenemases are members of the β-lactamases that are divid...See full text at original site
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引用元:
https://doi.org/10.1016/j.ijantimicag.2022.106528

データ提供:米国国立医学図書館(NLM)

Fighting the Rise of Carbapenemase-Producing Enterobacterales

The emergence of carbapenem resistance in Enterobacterales, a formidable foe in the battle against bacterial infections, has become a pressing public health concern. This research, akin to a seasoned desert warrior mapping out a strategic defense, delves into the complexities of carbapenemase-producing Enterobacterales (CPE), examining recent advances in diagnosis and treatment. The authors provide a comprehensive overview of carbapenemases, their classification, and the challenges associated with their increasing prevalence. They also explore a range of novel agents that have been approved for clinical use, offering potential solutions to this formidable foe. The research highlights the importance of accurate and rapid diagnosis, emphasizing the need for advanced diagnostic methods, akin to a sharp desert warrior's keen eyesight, to effectively combat this growing threat.

The Importance of Rapid and Accurate Diagnosis

The study emphasizes the critical need for accurate and rapid diagnosis of CPE infections, akin to a desert warrior's ability to quickly identify and react to an approaching threat. The authors review a range of diagnostic methods, including phenotypic, biochemical, immunochromatographic, proteomic, and molecular-based techniques, highlighting their strengths and limitations. This comprehensive overview provides a roadmap for clinicians to effectively identify CPE, enabling them to implement appropriate treatment strategies and prevent the spread of these resistant bacteria. The research underscores the crucial role of timely and precise diagnosis in the fight against antibiotic resistance, a battle as fierce and relentless as a desert sandstorm.

The Ongoing Battle Against Antibiotic Resistance

The emergence of CPE poses a significant challenge to public health, akin to a formidable sandstorm threatening a desert oasis. This research provides a valuable guide to navigating this complex landscape, emphasizing the need for both accurate diagnosis and effective treatment strategies. The authors highlight the importance of developing new antibiotics and diagnostic methods to counter the growing threat of antibiotic resistance, a challenge as vast and relentless as the desert itself. The quest for effective solutions continues, fueled by the relentless pursuit of researchers who are determined to protect our health and well-being.

Dr. Camel's Conclusion

The fight against carbapenemase-producing Enterobacterales is an ongoing battle, as challenging and complex as navigating a vast and unforgiving desert. This research provides valuable insights into this formidable foe, emphasizing the need for accurate and rapid diagnosis, as well as the development of new treatment strategies. The quest for effective solutions continues, fueled by the determination of researchers who are committed to safeguarding our health and well-being.

Date :
  1. Date Completed 2022-03-16
  2. Date Revised 2022-03-16
Further Info :

Pubmed ID

35063651

DOI: Digital Object Identifier

10.1016/j.ijantimicag.2022.106528

Related Literature

SNS
PICO Info
in preparation
Languages

English

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