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Short Intravenous Antibiotic Courses for Urinary Infections in Young Infants: A Systematic Review.

Author: GweeAmanda, HikmatSamar, LawrenceJolie

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This systematic review investigated the optimal duration of intravenous (IV) antibiotic treatment for urinary tract infections (UTIs) in infants aged ≤90 days. The study found that shorter IV antibiotic courses of ≤7 days and ≤3 days with early switch to oral antibiotics were appropriate for bacteremic and nonbacteremic UTIs, respectively. Further research is needed to evaluate the safety and effectiveness of oral antibiotics alone for UTIs in this age group.
Paper Details　
Original Abstract of the Article :
CONTEXT: Urinary tract infections (UTIs) are common in young infants, yet there is no guidance on the optimal duration of intravenous (IV) treatment. OBJECTIVE: To determine if shorter IV antibiotic courses (≤7 days) are appropriate for managing UTIs in infants aged ≤90 days. METHODS: PubMed, the ...See full text at original site
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引用元：
https://doi.org/10.1542/peds.2021-052466

データ提供：米国国立医学図書館（NLM）

Short Intravenous Antibiotic Courses for Urinary Infections in Infants: A Systematic Review

This systematic review examines the optimal [duration of intravenous (IV) antibiotic treatment] for [urinary tract infections (UTIs)] in [young infants]. The authors conducted a comprehensive review of [published studies] to assess the [efficacy] and [safety] of [short IV antibiotic courses] compared to [standard durations] in infants aged ≤90 days. Their findings suggest that [shorter IV courses] may be appropriate for both [bacteremic UTIs] and [nonbacteremic UTIs] in this age group, potentially reducing the [risk of adverse events] associated with prolonged IV therapy.

Navigating Antibiotic Therapy for Infants: A Balancing Act

This study underscores the importance of [evidence-based decision-making] in [antibiotic therapy] for [infants]. The authors highlight the potential benefits of [shorter IV courses] in reducing [treatment duration] and [risk of side effects], while also emphasizing the need for [careful monitoring] and [early switch to oral antibiotics] when appropriate.

Urinary Tract Infections in Infants: A Focus on Safe and Effective Treatment

This research highlights the crucial role of [appropriate antibiotic management] in preventing [complications] and ensuring [optimal outcomes] in infants with [UTIs]. The authors' findings provide valuable guidance for healthcare providers in choosing the most effective and safe treatment strategies for this vulnerable population.

Dr.Camel's Conclusion

This study underscores the need for a [more nuanced approach] to [antibiotic treatment] for [infants with UTIs], suggesting that shorter IV courses may be safe and effective. Just as a camel adapts to the changing conditions of the desert, healthcare providers must adapt to the evolving landscape of antibiotic therapy, finding the right balance between effectiveness and safety for infants. This research is a reminder that the goal is to provide the most appropriate care possible, minimizing risks and maximizing outcomes.

Date :
  1. Date Completed 2022-02-21
  2. Date Revised 2022-02-21
Further Info :

Pubmed ID

35075480

DOI: Digital Object Identifier

10.1542/peds.2021-052466

Related Literature

Article Analysis
・Effective treatment of urinary tract infections
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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