Paper Details

  1. Home
  2. Paper Details

A Case of Vogt-Koyanagi-Harada Disease-Like Uveitis Induced by Nivolumab and Ipilimumab Combination Therapy.

Author: EgawaMariko, KajitaKeisuke, MinamiKeisuke, MitamuraYoshinori, MuraoFumiko

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.

Overview

This case report describes a patient with advanced melanoma who experienced recurrent Vogt-Koyanagi-Harada (VKH) disease-like uveitis after resuming nivolumab and ipilimumab treatment.
Paper Details　
Original Abstract of the Article :
Nivolumab and ipilimumab are widely used immune checkpoint inhibitors (ICPIs) for the treatment of metastatic melanoma. ICPIs cause an array of side effects called immune-related adverse events (IRAEs) due to activation of an immune response. ICPI-uveitis can cause irreversible vision loss if untrea...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740278/

データ提供：米国国立医学図書館（NLM）

Immune Checkpoint Inhibitors: Navigating the Desert of Immune-Related Adverse Events

Immune checkpoint inhibitors (ICPIs) are powerful weapons in the fight against cancer, but they can sometimes trigger immune-related adverse events (IRAEs), like unexpected sandstorms in the desert of our immune system. This case report highlights the potential for ICPIs to cause uveitis, a condition that affects the eye. The patient experienced a recurrence of uveitis after resuming ICPI treatment, highlighting the importance of careful monitoring for IRAEs.

Monitoring for IRAEs: A Vital Compass in the Desert of Cancer Treatment

The case report emphasizes the importance of vigilant monitoring for IRAEs in patients receiving ICPI treatment. It's like having a reliable compass to navigate the sometimes unpredictable terrain of cancer treatment.

Early Detection and Intervention: A Key to Protecting Vision

The case report underscores the importance of early detection and intervention in managing IRAEs, particularly those that affect vision. It's like having a vigilant lookout to spot potential sandstorms and take timely action to protect our eyesight.

Dr.Camel's Conclusion

This case report reminds us that the desert of cancer treatment can be complex and unpredictable. It highlights the importance of careful monitoring for IRAEs and prompt intervention to minimize potential complications.

Date :
  1. Date Completed n.d.
  2. Date Revised 2022-01-28
Further Info :

Pubmed ID

35082654

DOI: Digital Object Identifier

PMC8740278

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.