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Appropriate duration of antithyroid drug treatment as a predictor for relapse of Graves' disease: a systematic scoping review.

Author: AbdiH, AmouzegarA, AziziF, MehranL

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This systematic scoping review critically appraised the duration of antithyroid drug (ATD) therapy for Graves' disease (GD) over the past 80 years. The review highlighted the evolution of ATD therapy, with longer treatment durations becoming more common. Long-term ATD treatment for more than 60 months was found to be safe and effective, offering the highest remission rate and potentially curing most patients with GD.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Following the conventional 12-18 month antithyroid drug (ATD) treatment in Graves' disease (GD), 50% of patients experience relapse of hyperthyroidism. OBJECTIVE: The aim of this systematic scoping review was critical appraisal of duration of ATD therapy in the last 80 years. METHODS: ...See full text at original site
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引用元：
https://doi.org/10.1007/s40618-021-01730-1

データ提供：米国国立医学図書館（NLM）

Appropriate Duration of Antithyroid Drug Treatment

This research takes us on a journey through the world of Graves' disease, a condition that can be as challenging to manage as a desert oasis that requires careful attention to maintain its delicate balance. The study explores the appropriate duration of antithyroid drug (ATD) treatment for Graves' disease and examines the factors that influence the risk of relapse. It's like studying the optimal time to harvest dates from a palm tree, ensuring a sustainable and successful yield.

Exploring the Duration of ATD Therapy

The researchers conducted a systematic scoping review of the literature to assess the historical evolution of ATD therapy for Graves' disease. They examined the duration of treatment, the effectiveness of different drugs, and the factors that influence the likelihood of relapse. It's like tracing the history of irrigation techniques in a desert, understanding the evolution of strategies for managing water resources.

Optimizing Treatment for Graves' Disease

The study found that long-term ATD therapy for more than 60 months can be safe and effective, offering the highest remission rate and potentially curing most patients with Graves' disease. It's like finding a reliable source of water in a desert, providing a long-term solution for sustaining life. This research offers valuable insights for doctors seeking to optimize treatment for Graves' disease, ensuring a more stable and sustainable recovery for their patients.

Dr.Camel's Conclusion

The study of ATD therapy for Graves' disease is a journey through a desert of complex endocrine disorders. It highlights the importance of considering the long-term implications of treatment decisions and finding the optimal approach to managing this challenging condition. This research reminds us that even in the face of complex medical challenges, we can find solutions that offer hope for a healthier future.

Date :
  1. Date Completed 2022-05-17
  2. Date Revised 2022-05-17
Further Info :

Pubmed ID

35088381

DOI: Digital Object Identifier

10.1007/s40618-021-01730-1

SNS
PICO Info
in preparation
Languages

English

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