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Gastroprotective effect of low dose Eugenol in experimental rats against ethanol induced toxicity: Involvement of antiinflammatory and antioxidant mechanism.

Author: AbdelhaleemAymen, Abou-ElhamdAlaa Sayed, BhatiaSaurabh, Faruque AhmadMd, HobaniYahya Hasan, MohanSyam, ShaheenEmad

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Clove oil, containing eugenol as its main component, has traditional uses for stomach disorders. While eugenol has shown gastroprotective effects, its precise mechanism is not fully understood. This review explores the complex effects of eugenol on ulcer protection, highlighting its potential benefits at lower doses and detrimental effects at higher doses.
Paper Details　
Original Abstract of the Article :
Syzygium aromaticum L. volatile oil (clove oil) has been traditionally used for various stomach disorders including inflammatory conditions. Eugenol is the major constituent present in the volatile oil, and it has been established as a gastroprotective agent through many published studies, but the e...See full text at original site
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引用元：
https://doi.org/10.1016/j.jep.2022.115055

データ提供：米国国立医学図書館（NLM）

Eugenol: A Potential Protector Against Ethanol-Induced Stomach Damage

The delicate balance of gut health is like a fragile oasis in a vast desert, susceptible to various threats. This research, like a vigilant camel guarding a precious water source, explores the gastroprotective effects of eugenol, a compound found in clove oil, against ethanol-induced stomach damage. The researchers investigated the mechanism by which eugenol protects the stomach lining, discovering that it exerts its protective effects through its anti-inflammatory and antioxidant properties. These findings offer a potential new avenue for treating and preventing ethanol-induced stomach damage.

Eugenol's Gastroprotective Potential: A Glimmer of Hope

The study's findings highlight the potential of eugenol as a gastroprotective agent. Its ability to protect the stomach lining from ethanol-induced damage suggests that it could play a role in preventing and treating gastritis and ulcers. This discovery could lead to the development of new therapies for gastrointestinal health, offering a more natural and effective approach to managing these conditions.

Navigating the Desert of Gut Health

This research emphasizes the importance of understanding the delicate balance of gut health and the potential of natural compounds to play a role in maintaining this balance. The study's findings encourage further exploration of eugenol and other natural substances with potential gastroprotective properties. This research could lead to new insights into the prevention and treatment of gastrointestinal diseases, offering a more holistic approach to gut health.

Dr.Camel's Conclusion

This research reveals the potential of eugenol, a natural compound found in clove oil, to protect the stomach lining from ethanol-induced damage. Its anti-inflammatory and antioxidant properties suggest a promising new avenue for treating and preventing gastrointestinal disorders. While further research is needed to fully understand the mechanisms and clinical applications of eugenol, this study offers a glimmer of hope for a more natural and effective approach to maintaining gut health.

Date :
  1. Date Completed 2022-03-14
  2. Date Revised 2022-03-14
Further Info :

Pubmed ID

35101571

DOI: Digital Object Identifier

10.1016/j.jep.2022.115055

Related Literature

Article Analysis
・Effective treatment of stomach disorders
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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