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Impact of leukoaraiosis in patients with acute ischemic stroke treated with thrombectomy: a post hoc analysis of the DIRECT-MT trial.

Author: , CaiMing-Zhi, ChenWen-Huo, LiTianxiao, LinDing-Lai, LinXiao-Hui, LiuJianmin, WangShouchun, WuYan-Min, XingPeng-Fei, YangPengfei, YiTingyu, ZhangLei, ZhangYongwei, ZhangYongxin

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Patients with leukoaraiosis (a common brain abnormality) who experience acute ischemic stroke have an increased risk of poor functional outcome following intra-arterial treatment. However, there was no increased risk of symptomatic intracranial hemorrhage with or without intravenous thrombolysis preceding intra-arterial treatment.
Paper Details　
Original Abstract of the Article :
BACKGROUND: The influence of leukoaraiosis in patients with acute ischemic stroke (AIS) given intra-arterial treatment (IAT) with or without preceding intravenous thrombolysis (IVT) remains unknown. OBJECTIVE: To assess the clinical and radiological outcomes of IAT in patients with or without leuko...See full text at original site
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引用元：
https://doi.org/10.1136/neurintsurg-2021-018293

データ提供：米国国立医学図書館（NLM）

Leukoaraiosis and Thrombectomy Outcomes in Acute Ischemic Stroke

The world of stroke treatment, like a vast desert landscape, is filled with complexities and challenges. This study focuses on the interplay between leukoaraiosis, a condition characterized by white matter lesions in the brain, and the effectiveness of thrombectomy, a procedure to remove blood clots from arteries, in patients with acute ischemic stroke. The authors meticulously analyzed data from a large clinical trial to investigate this relationship.

Their findings, like a clear path through the desert, reveal that patients with leukoaraiosis face a higher risk of poor functional outcomes after thrombectomy, despite similar rates of bleeding complications. This suggests that leukoaraiosis could be a significant factor to consider when planning stroke treatment strategies.

Navigating Stroke Treatment: The Importance of Leukoaraiosis

This study highlights the importance of considering leukoaraiosis when treating patients with acute ischemic stroke. Leukoaraiosis, like a hidden sandstorm, can affect the effectiveness of thrombectomy. This emphasizes the need for personalized treatment plans tailored to individual patient characteristics.

Understanding Stroke Recovery: The Role of Leukoaraiosis

This research, like a guiding star illuminating the path to recovery, sheds light on the impact of leukoaraiosis on stroke outcomes. It is a reminder that each patient's journey is unique and requires a comprehensive understanding of their individual condition for the best possible care.

Dr.Camel's Conclusion

This study, like a camel caravan traversing a vast desert landscape, navigates the complex terrain of stroke treatment, highlighting the crucial role of leukoaraiosis in influencing outcomes. It underscores the need for a nuanced understanding of individual patient characteristics to guide optimal treatment strategies and promote successful recovery.

Date :
  1. Date Completed 2023-01-13
  2. Date Revised 2023-01-13
Further Info :

Pubmed ID

35101958

DOI: Digital Object Identifier

10.1136/neurintsurg-2021-018293

Related Literature

Article Analysis
・Effective treatment of ischemic stroke
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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