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Original Abstract of the Article :
A double-blind multicenter study compared oral acebutolol (n = 182) with hydrochlorothiazide (n = 178) in the treatment of mild to moderate essential hypertension (diastolic blood pressure 95 to 114 mm Hg). Both agents produced significant and comparable reductions in systolic, diastolic, and mean a...See full text at original site
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引用元:
https://doi.org/10.1016/0002-8703(86)90153-5
データ提供:米国国立医学図書館(NLM)
Acebutolol vs Hydrochlorothiazide: A Head-to-Head Comparison for Hypertension
The world of [hypertension] is a vast and complex landscape, where finding the right medication is crucial for managing this prevalent condition. This study compares the effectiveness and tolerability of two commonly used [antihypertensive drugs]: [acebutolol] and [hydrochlorothiazide]. The researchers conducted a [double-blind multicenter study] to evaluate the impact of these drugs on [blood pressure] and [heart rate] in patients with [mild to moderate essential hypertension], much like a desert explorer carefully comparing different routes to find the most suitable path.
Acebutolol and Hydrochlorothiazide: Comparable Effectiveness in Hypertension
The study found that both [acebutolol] and [hydrochlorothiazide] produced significant and comparable reductions in [blood pressure], suggesting that both drugs are effective in managing [hypertension]. However, [acebutolol] was associated with fewer [adverse events], particularly [arrhythmia, anorexia, and flatulence]. These findings suggest that [acebutolol] might be a more tolerable option for some patients, much like a desert traveler might choose a path with fewer obstacles and a more comfortable terrain.
Navigating Hypertension Treatment: Considerations for Acebutolol and Hydrochlorothiazide
This study provides valuable information for physicians and patients who are managing [hypertension]. While both [acebutolol] and [hydrochlorothiazide] are effective in reducing [blood pressure], [acebutolol] may offer a more favorable [side effect profile] for some individuals. The choice of medication should be made on a case-by-case basis, considering the patient's individual [medical history], [risk factors], and [preferences]. It's like navigating a desert landscape, where the optimal route depends on the individual traveler's strengths, weaknesses, and goals.
Dr. Camel's Conclusion
This study highlights the importance of carefully considering [side effect profiles] when choosing [antihypertensive medications]. While both [acebutolol] and [hydrochlorothiazide] are effective in managing [hypertension], [acebutolol] may offer a more tolerable option for some patients. It's a reminder that the journey of managing [hypertension] is not a one-size-fits-all approach, and finding the right medication for each individual is key to success.
Date :
- Date Completed 1986-03-10
- Date Revised 2019-06-26
Further Info :
Related Literature
English
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