Neoadjuvant and adjuvant treatment of patients with HER2-positive early breast cancer.

Author: HarbeckNadia

Paper Details 
Original Abstract of the Article :
The availability of HER2-targeted therapy has dramatically improved patient outcome in HER2-positive (HER2+) early breast cancer (EBC) as recently demonstrated by the EBCTCTG metaanalysis on trastuzumab in HER2+ EBC: Adding trastuzumab to chemotherapy has reduced recurrence rates and breast-cancer r...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097807/

データ提供:米国国立医学図書館(NLM)

HER2-Positive Early Breast Cancer: A New Era of Treatment

HER2-positive (HER2+) early breast cancer (EBC) poses a significant challenge in oncology. This research provides a comprehensive overview of the evolving landscape of neoadjuvant and adjuvant treatment for HER2+ EBC, highlighting the remarkable advancements in targeted therapies and the growing importance of personalized treatment approaches. The authors discuss the pivotal role of HER2-targeted therapy in improving patient outcomes, specifically focusing on trastuzumab and its impact on reducing recurrence rates and mortality. They also emphasize the increasing use of neoadjuvant therapy and the significance of achieving pathological complete response (pCR) as a predictor of favorable outcomes. The research underscores the need for multidisciplinary care and ongoing research to further optimize treatment strategies for HER2+ EBC.

Personalized Treatment for HER2+ EBC: A Collaborative Effort

The study's findings highlight the importance of personalized treatment approaches for HER2+ EBC, considering individual patient characteristics and tailoring therapy to achieve optimal outcomes. It emphasizes the need for a multidisciplinary team, including oncologists, surgeons, pathologists, and other specialists, to work collaboratively in developing individualized treatment plans.

Hope for HER2+ EBC Patients: Continual Advancements in Treatment

The research provides a hopeful outlook for individuals with HER2+ EBC, highlighting the ongoing advancements in targeted therapies and the increasing focus on personalized treatment approaches. It emphasizes the need for continued research and development to further improve treatment outcomes and enhance the lives of patients with this challenging condition.

Dr.Camel's Conclusion

This research showcases the remarkable progress made in the treatment of HER2+ EBC, highlighting the impact of targeted therapies and the importance of personalized medicine. It underscores the need for continued research and innovation to further refine treatment strategies and improve outcomes for patients with this challenging condition. The journey towards better breast cancer treatment is ongoing, and we can be optimistic about the future, fueled by the relentless pursuit of improved therapies and personalized care.

Date :
  1. Date Completed 2022-04-28
  2. Date Revised 2022-07-16
Further Info :

Pubmed ID

35148934

DOI: Digital Object Identifier

PMC9097807

Related Literature

SNS
PICO Info
in preparation
Languages

English

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