Efficacy of and adverse effects of disopyramide. Comparison of capsules, controlled release tablets and placebo in patients with chronic ventricular arrhythmias.

Author: EkelundL G, NilssonE, WalldiusG

Paper Details 
Original Abstract of the Article :
The efficacy of disopyramide compared to placebo for exercise induced ventricular arrhythmias was tested in a double-blind randomized controlled clinical trial with cross-over design in 14 patients with coronary heart disease. Disopyramide was given as ordinary capsules (q.i.d.) or as a slow release...See full text at original site
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引用元:
https://doi.org/10.1007/BF00615957

データ提供:米国国立医学図書館(NLM)

Disopyramide: A Camel's Tale of Arrhythmia Control

Cardiovascular research is a vast desert, filled with mysteries waiting to be unraveled. This study, exploring the efficacy and safety of disopyramide for treating chronic ventricular arrhythmias, is like finding an oasis in the middle of this desert. The researchers used a double-blind, randomized controlled clinical trial with a crossover design to compare disopyramide capsules, controlled-release tablets, and a placebo in 14 patients with coronary heart disease. This meticulous approach ensured that the researchers were truly comparing apples to apples.

Disopyramide - A Promising Oasis in the Desert of Arrhythmias

Their findings were as clear as the desert sky after a rainstorm: disopyramide effectively reduced ventricular ectopic beats, both at rest and during exercise. The researchers observed no significant difference in effectiveness between the capsule and tablet formulations. These findings offer hope for patients struggling with these irregular heartbeats.

Disopyramide: A Safe Journey through the Cardiac Desert

The researchers also found that disopyramide was well-tolerated, with only mild side effects such as anticholinergic symptoms, which were similar for both preparations. These findings suggest that disopyramide can be a safe and effective treatment option for patients with chronic ventricular arrhythmias.

Dr. Camel's Conclusion

This study sheds light on the potential of disopyramide as a valuable treatment option for chronic ventricular arrhythmias. As a camel who has traversed many a desert, I can attest to the importance of finding reliable and effective solutions. This research provides a beacon of hope for those seeking relief from this condition.

Date :
  1. Date Completed 1986-07-24
  2. Date Revised 2019-08-13
Further Info :

Pubmed ID

3519236

DOI: Digital Object Identifier

10.1007/BF00615957

Related Literature

SNS
PICO Info
in preparation
Languages

English

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