Results of another trial of chemotherapy with and without hormones in patients with newly diagnosed metastatic prostate cancer.

Author: HubenR P, MurphyG P, PrioreR

Paper Details 
Original Abstract of the Article :
From July, 1980, to June, 1983, 319 patients with newly diagnosed metastatic prostatic cancer were randomized to one of three treatment protocols: diethylstilbestrol (DES) or bilateral orchiectomy, cyclophosphamide plus 5-fluorouracil plus DES, and estramustine phosphate (Emcyt). Ninety-three per ce...See full text at original site
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引用元:
https://doi.org/10.1016/0090-4295(86)90178-0

データ提供:米国国立医学図書館(NLM)

Chemotherapy and Hormones: A Clinical Trial in Prostate Cancer

The world of medicine is constantly searching for effective treatments for prostate cancer. This research investigated the impact of chemotherapy, with and without hormones, in patients newly diagnosed with metastatic prostate cancer. They conducted a randomized clinical trial to compare three treatment protocols: diethylstilbestrol (DES) or bilateral orchiectomy, cyclophosphamide plus 5-fluorouracil plus DES, and estramustine phosphate (Emcyt). This research explores the effectiveness of these treatments and seeks to understand if there are any significant differences in their outcomes.

No Clear Advantage

The study found no significant differences in survival, disease-free progression time, or pain relief between the treatment groups. This suggests that all three protocols may have similar efficacy in treating metastatic prostate cancer. It's like a camel searching for the best oasis in the desert, finding that each oasis holds its own unique charm but ultimately provides similar sustenance.

Navigating Prostate Cancer Treatment

While the study did not find clear advantages of one treatment over another, it provides valuable information for patients and their doctors. It highlights the importance of individualizing treatment plans based on each patient's unique situation. Understanding these factors can guide doctors in choosing the best course of treatment for each patient, ensuring the most effective and personalized approach to battling this disease. It is like a camel navigating a vast and intricate sand dune landscape, adapting its path to each individual challenge.

Dr.Camel's Conclusion

This study emphasizes the need for continued research into prostate cancer treatments. While no clear advantage was found between the three protocols, the results provide valuable insights into the complex nature of this disease. This research encourages further investigation into personalized approaches to treatment, taking into account individual patient characteristics. It is like a camel traversing the desert, constantly seeking new knowledge and pathways to navigate the challenges of prostate cancer.

Date :
  1. Date Completed 1986-08-08
  2. Date Revised 2019-07-13
Further Info :

Pubmed ID

3523938

DOI: Digital Object Identifier

10.1016/0090-4295(86)90178-0

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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