Ketamine in the Treatment of Obsessive-Compulsive Disorder: A Systematic Review.

Author: BandeiraIgor D, BarouhJudah L, BeanesGraziele, CavenaghiVitor Breseghello, Dorea-BandeiraIngrid, Faria-GuimarãesDaniela, Jesus-NunesAna Paula, LealGustavo C, Lins-SilvaDaniel H, MiguelEuripedes C, QuarantiniLucas C, SampaioAline S, SanacoraGerard, SouzaLucca S

Paper Details 
Original Abstract of the Article :
First-line treatment for obsessive-compulsive disorder (OCD) includes exposure and response prevention behavioral therapy and serotonin reuptake inhibitors, particularly in combination. New and more effective treatments are needed, give that recent studies suggest that glutamatergic neurotransmissio...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/35267254

データ提供:米国国立医学図書館(NLM)

Ketamine: A Potential New Treatment for Obsessive-Compulsive Disorder

Obsessive-compulsive disorder (OCD) is a mental health condition that affects millions of people worldwide, characterized by intrusive thoughts and repetitive behaviors. This research explores the potential of ketamine, a drug typically used as an anesthetic, as a novel treatment for OCD.

The study reviewed the existing literature on ketamine and its effects on OCD, focusing on the role of glutamatergic neurotransmission (communication between nerve cells) in the disorder. The authors suggest that ketamine, a potent N-methyl-D-aspartate receptor antagonist (a type of glutamate blocker), might offer alternative treatment options for OCD, particularly considering the emerging evidence linking glutamatergic neurotransmission to the development of the disorder.

New Hope for Treatment

The study's findings suggest that ketamine, through its modulation of glutamate activity, could potentially offer an effective treatment for OCD, providing a new avenue for managing this challenging disorder. However, further research is needed to determine the safety and efficacy of ketamine specifically for OCD treatment.

Exploring New Therapeutic Avenues

This research highlights the importance of exploring innovative approaches to treating mental health conditions, especially in light of the ongoing search for more effective treatments for OCD. By examining the role of glutamate and its modulation by ketamine, the study opens new doors for understanding the underlying mechanisms of OCD and developing novel therapies.

Dr.Camel's Conclusion

Just as a camel adapts to its desert surroundings, we must adapt our approach to treating mental health conditions. This research suggests that ketamine, a seemingly unlikely candidate, may hold promise for OCD treatment, demonstrating the importance of exploring new horizons in medicine.

Date :
  1. Date Completed 2022-04-19
  2. Date Revised 2022-12-07
Further Info :

Pubmed ID

35267254

DOI: Digital Object Identifier

00023727-202203000-00004

SNS
PICO Info
in preparation
Languages

English

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