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Low-dose methotrexate in rheumatoid arthritis: effect and tolerance. An open trial and a double-blind randomized study.

Author: SzantoE

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Weekly low-dose methotrexate (MTX) is a safe and effective treatment option for patients with severe rheumatoid arthritis (RA) who have not responded to conventional therapies. While long-term studies are needed to confirm its impact on joint damage, MTX has shown promise in slowing the progression of RA. However, potential side effects should be monitored closely.
Paper Details　
Original Abstract of the Article :
Weekly low-dose Mtx may be considered the preferred drug for the treatment of patients with severe, progressive RA resistant to conventional therapy. The drug is sufficiently safe, provided contra-indications are considered and treatment is carefully supervised. Controlled long-term prospective stud...See full text at original site
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引用元：
https://doi.org/10.3109/03009748609102072

データ提供：米国国立医学図書館（NLM）

Methotrexate: A Potential Solution for Rheumatoid Arthritis

This research explores the efficacy and safety of [methotrexate] as a treatment option for [rheumatoid arthritis (RA)]. The study examines the use of low-dose methotrexate in patients with severe, progressive RA resistant to conventional therapies. The researchers found that methotrexate can be a safe and effective treatment option for RA, provided proper contraindications are considered and careful monitoring is implemented.

Low-Dose Methotrexate: A Promising Therapeutic Approach

The research highlights the potential of low-dose methotrexate in managing RA. The study's findings suggest that methotrexate can be a valuable treatment option for patients with severe and progressive RA, particularly those who haven't responded well to conventional therapies. However, the researchers emphasize the importance of careful monitoring and adherence to appropriate protocols to ensure patient safety.

Managing Rheumatoid Arthritis: Balancing Benefits and Risks

This research sheds light on the ongoing quest for effective and safe treatments for rheumatoid arthritis. The study's findings suggest that low-dose methotrexate can be a viable option for some patients, but careful monitoring and consideration of potential side effects are crucial. The researchers call for further research to evaluate the long-term effects of methotrexate and explore alternative therapeutic approaches that may provide even greater benefits for patients.

Dr.Camel's Conclusion

This research delves into the challenging world of rheumatoid arthritis, providing insights into the potential benefits and risks of methotrexate as a treatment option. The study emphasizes the need for careful monitoring and individualized care, highlighting the importance of a multidisciplinary approach to managing this complex condition. This research serves as a reminder that the search for effective and safe treatments for RA continues, demanding ongoing research and collaboration between healthcare professionals and patients.

Date :
  1. Date Completed 1986-10-06
  2. Date Revised 2019-09-08
Further Info :

Pubmed ID

3529375

DOI: Digital Object Identifier

10.3109/03009748609102072

Related Literature

Article Analysis
・Effective treatment of arthritis
SNS
PICO Info
in preparation
Languages

English

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