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Gastric ulcer: a double-blind comparison of 100 mg pirenzepine plus antacid versus 800 mg cimetidine plus antacid.

Author: ArnoldJ, BirchlerR, BretholzA, CapitaineY, GonversJ J, GuyotJ, OllyoJ B, RealiniS, VoirolM

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Cimetidine and pirenzepine were equally effective in healing gastric ulcers. The most common side effects were mild and did not differ from those observed in other studies.
Paper Details　
Original Abstract of the Article :
Fifty-five patients with endoscopically confirmed gastric ulcers received either cimetidine (28 patients) or pirenzepine (27 patients) in a randomized double-blind manner. Fifty-seven per cent of the patients treated with cimetidine and 48% of those treated with pirenzepine presented with endoscopic...See full text at original site
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引用元：
https://doi.org/10.3109/00365528609011121

データ提供：米国国立医学図書館（NLM）

Gastric Ulcers: A Comparison of Cimetidine and Pirenzepine

Gastric ulcers, like scorching desert sands, can cause significant pain and discomfort. This study, like a thirsty traveler seeking relief in the desert, compares the effectiveness of two medications, cimetidine and pirenzepine, in treating gastric ulcers.

A Desert Oasis for Gastric Ulcers: Comparing Treatment Options

The researchers conducted a double-blind randomized controlled trial, comparing the healing rates of cimetidine and pirenzepine in patients with endoscopically confirmed gastric ulcers. The results, like a refreshing oasis in the desert, show similar healing rates for both medications.

Navigating the Desert of Gastric Ulcers: A Balanced Approach

The study highlights the importance of considering individual patient characteristics, such as the severity of pain, when selecting treatment options for gastric ulcers. It also emphasizes the need for ongoing research to explore new and effective treatment approaches for this common and challenging condition.

Dr. Camel's Conclusion

This study provides valuable insights into the effectiveness of cimetidine and pirenzepine in treating gastric ulcers. Both medications demonstrate similar healing rates, highlighting the need for a personalized approach to treatment based on individual patient characteristics.

Date :
  1. Date Completed 1986-12-01
  2. Date Revised 2019-08-14
Further Info :

Pubmed ID

3535007

DOI: Digital Object Identifier

10.3109/00365528609011121

Related Literature

Article Analysis
・Effects of cimetidine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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