Efficacy of sintilimab and fruquintinib combination treatment in the management of microsatellite-stable metastatic colorectal cancer: a case report.

Author: ChenWeiyi, ChenZhuangzhong, JiangMei, LiangJiaqi, LinSen, ZhongLing

Paper Details 
Original Abstract of the Article :
The immune microenvironment of deficient mismatch repair or microsatellite instability-high (dMMR/MSI-H) colorectal cancer exhibits better immune activity, and patients with dMMR/MSI-H colorectal cancer benefit from immunotherapy with programmed death-1 (PD-1)/PD-1 ligand (PD-L1) inhibitors and cyto...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9011267/

データ提供:米国国立医学図書館(NLM)

Combating Microsatellite-Stable Metastatic Colorectal Cancer: A Case Report

The field of [oncology] is making significant strides in understanding and treating [colorectal cancer]. Immunotherapy has shown promise for patients with [deficient mismatch repair or microsatellite instability-high (dMMR/MSI-H) colorectal cancer], but the majority of cases are [microsatellite-stable (MSS)], presenting a greater challenge. This case report explores the efficacy of a combination therapy involving [sintilimab] and [fruquintinib] in a patient with MSS metastatic colorectal cancer.

A Promising Combination Therapy

This case report provides evidence that the combination of [sintilimab] and [fruquintinib] may be an effective treatment option for [microsatellite-stable (MSS) metastatic colorectal cancer] in patients who have failed multiple lines of chemotherapy. This finding offers hope for patients with MSS metastatic colorectal cancer who have limited treatment options. Further research is needed to assess the efficacy and safety of this combination therapy in larger patient populations.

New Hope for a Difficult Disease

This case report provides a glimmer of hope in the fight against [microsatellite-stable (MSS) metastatic colorectal cancer]. It's like discovering a hidden spring in the desert, offering a source of hydration and sustenance for those facing a challenging journey. This research inspires us to continue exploring new treatment options for this challenging disease, ultimately striving to improve patient outcomes and enhance quality of life.

Dr.Camel's Conclusion

This case report highlights the importance of persistent research and innovation in the field of oncology. It's like a camel caravan traveling through the desert, constantly seeking new paths and strategies to overcome obstacles and reach their destination. This research encourages us to remain hopeful and dedicated to finding better treatments for all patients with cancer.

Date :
  1. Date Completed n.d.
  2. Date Revised 2022-07-16
Further Info :

Pubmed ID

35433988

DOI: Digital Object Identifier

PMC9011267

Related Literature

SNS
PICO Info
in preparation
Languages

English

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