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Portable solid-state sensor for therapeutic monitoring of an antineoplastic drug; vinblastine in human plasma.
Author: GalalMaha Mohammed, SaadAhmed Sayed
Original Abstract of the Article :
During cancer treatment, doses must be carefully administered and monitored to guarantee efficacy and minimize side-effects. A potentiometric sensor was developed for the direct real-time assay of a widely used antineoplastic drug (vinblastine (VB)) in plasma samples. Membrane cocktails were drop-ca...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9058239/
データ提供:米国国立医学図書館(NLM)
A Sensor in the Desert: Monitoring Vinblastine in Cancer Treatment
The vast desert of cancer treatment demands precise navigation. Ensuring the right dose of chemotherapy drugs is crucial, as too little won't work, and too much can be dangerous. This research introduces a novel solid-state sensor for monitoring vinblastine, a widely used antineoplastic drug, in human plasma. The researchers crafted this sensor with a glassy-carbon electrode coated with a lipophilic conducting polymer and a carefully curated membrane cocktail. Their goal is to create a reliable and efficient tool for real-time monitoring of vinblastine levels, guiding clinicians toward the optimal treatment path.
A Guiding Star in the Sands of Chemotherapy
The results of this study demonstrate the feasibility of developing a portable solid-state sensor for direct and real-time monitoring of vinblastine levels. This sensor has a fast response, high sensitivity, and excellent selectivity, making it a valuable tool for optimizing chemotherapy treatment. The researchers successfully demonstrated the sensor's effectiveness in various applications, including the analysis of pure vinblastine powder, marketed formulations, and human plasma samples.
A More Accurate and Efficient Journey
This research has the potential to revolutionize chemotherapy monitoring, enabling clinicians to adjust treatment plans based on real-time data. This could lead to more effective and personalized therapies, minimizing side effects and maximizing therapeutic outcomes. This sensor is a promising new tool in the battle against cancer, making the journey through the desert of treatment a bit more manageable.
Dr.Camel's Conclusion
This sensor is like a trusty camel, providing a clear and reliable path through the desert of chemotherapy. Its ability to monitor vinblastine levels in real-time offers a crucial advantage in optimizing treatment plans. The future of cancer treatment looks brighter with this new innovation, potentially leading to more effective and personalized therapies for patients.
Date :
- Date Completed n.d.
- Date Revised 2022-07-16
Further Info :
Related Literature
English
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