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A Randomized Controlled Trial for Prevention of Postoperative Nausea and Vomiting after Laparoscopic Sleeve Gastrectomy: Aprepitant/Dexamethasone vs. Mirtazapine/Dexamethasone.

Author: AshoorTarek M, EsmatIbrahim M, KassimDina Y

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This clinical trial compared three different antiemetic combinations for preventing postoperative nausea and vomiting (PONV) after laparoscopic sleeve gastrectomy (LSG) in morbidly obese patients. The study found that the aprepitant/dexamethasone combination was more effective in preventing PONV compared to the mirtazapine/dexamethasone combination or dexamethasone alone. These findings provide evidence for the superior efficacy of aprepitant/dexamethasone in managing PONV following LSG.
Paper Details　
Original Abstract of the Article :
Label="Background" NlmCategory="UNASSIGNED">Coadministration of different antiemetics proved to decrease postoperative nausea and vomiting (PONV) after laparoscopic sleeve gastrectomy (LSG). This trial compared aprepitant/dexamethasone (A/D) combination vs mirtazapine/dexamethasone (M/D) combination...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078838/

データ提供：米国国立医学図書館（NLM）

Preventing Postoperative Nausea and Vomiting: Comparing Anti-Emetic Combinations

Postoperative nausea and vomiting (PONV) is a common and often unpleasant complication following surgery. This study compares two different anti-emetic combinations, aprepitant/dexamethasone (A/D) and mirtazapine/dexamethasone (M/D), in preventing PONV after laparoscopic sleeve gastrectomy (LSG). The researchers conducted a randomized controlled trial to determine which combination was more effective in reducing PONV incidence.

A/D vs. M/D: Comparing Anti-Emetic Combinations for PONV Prevention

The study found that the aprepitant/dexamethasone (A/D) combination was significantly more effective in preventing PONV compared to the mirtazapine/dexamethasone (M/D) combination. The A/D combination also showed a lower incidence of PONV compared to dexamethasone alone. These findings suggest that A/D may be a preferred option for preventing PONV following LSG.

Navigating Postoperative Discomfort: A Focus on Individualized Care

This research highlights the importance of individualizing treatment approaches for postoperative nausea and vomiting (PONV). The study demonstrates that different anti-emetic combinations can have varying levels of effectiveness in preventing this common complication. It's crucial to consult with a healthcare professional to determine the most appropriate anti-emetic strategy for each individual, based on their specific needs and medical history.

Dr.Camel's Conclusion

Like a wise camel navigating a scorching desert, we must carefully choose our path to minimize the discomfort of postoperative nausea and vomiting (PONV). This research sheds light on the potential benefits of specific anti-emetic combinations, offering valuable insights for a smoother journey towards recovery. Remember, every journey is unique, and finding the right solution for PONV requires careful consideration and guidance from healthcare professionals.

Date :
  1. Date Completed n.d.
  2. Date Revised 2022-07-16
Further Info :

Pubmed ID

35535050

DOI: Digital Object Identifier

PMC9078838

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SNS
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in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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