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Amoxicillin-clavulanate potassium compared with cefaclor for acute otitis media in infants and children.

Author: BassL W, BluestoneC D, BreckJ M, KaleidaP H, RocketteH E, RohnD D, UbingerE B, WolfsonJ H

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Overview

This study compared the effectiveness of amoxicillin-clavulanate potassium and cefaclor in treating ear infections in children. Both drugs were effective in clearing ear infections, but amoxicillin-clavulanate potassium caused more gastrointestinal side effects.
Paper Details　
Original Abstract of the Article :
One hundred thirty-three infants and children with documented acute otitis media (OM) were randomized to receive the oral suspension of either amoxicillin-clavulanate potassium or cefaclor. Beta-lactamase-producing bacteria were found in 10.9 and 14.5% of subjects treated with amoxicillin-clavulanat...See full text at original site
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引用元：
https://doi.org/10.1097/00006454-198703000-00013

データ提供：米国国立医学図書館（NLM）

Amoxicillin-Clavulanate Potassium Compared with Cefaclor for Acute Otitis Media in Infants and Children

Acute otitis media (AOM), a common infection of the middle ear, can be a painful and distressing experience for infants and children. This study, like a clinical trial navigating the desert of childhood infections, compares the effectiveness of two antibiotics, amoxicillin-clavulanate potassium and cefaclor, in treating AOM in infants and children. The researchers aimed to determine which medication, like a potent desert herb with healing properties, could effectively combat AOM and provide relief for young patients.

Treating AOM: Finding the Right Antibiotic for the Journey

The study found that both amoxicillin-clavulanate potassium and cefaclor were effective in resolving AOM, but amoxicillin-clavulanate potassium was associated with a higher incidence of side effects. This suggests that the choice of antibiotic for AOM, like selecting the right camel for a long desert journey, should be carefully considered, balancing the effectiveness of the medication with the potential for side effects. The study also highlights the importance of considering the individual needs of each patient when making treatment decisions.

Navigating the Landscape of AOM Treatment

The study provides valuable insights into the treatment of AOM, offering guidance for healthcare professionals navigating this common childhood infection. It highlights the importance of considering both the efficacy and the side effect profile of antibiotics when making treatment decisions. The study also underscores the need for ongoing research to develop new and effective treatments for AOM, ensuring that young patients receive the best possible care.

Dr.Camel's Conclusion

This research, like a caravan traversing the vast desert of childhood illnesses, compares the effectiveness of two antibiotics for treating AOM. The study highlights the importance of careful consideration when selecting an antibiotic, balancing efficacy with potential side effects. It serves as a reminder that the desert of infectious diseases is diverse, and that a thoughtful and personalized approach is essential to ensure the best outcomes for young patients.

Date :
  1. Date Completed 1987-06-15
  2. Date Revised 2019-08-18
Further Info :

Pubmed ID

3554125

DOI: Digital Object Identifier

10.1097/00006454-198703000-00013

Related Literature

Article Analysis
・Side Effects of cefaclor
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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