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Adverse perinatal outcomes associated with HAART and monotherapy.
Author: BrandonZoe, HemelaarJoris, JohnsonBradley, KirtleyShona, KumarendranMary, MurrayClaudia, PortwoodClara, SextonHarriet
Original Abstract of the Article :
OBJECTIVES: Assess adverse perinatal outcomes in pregnant women living with HIV (WLHIV) receiving HAART or zidovudine (ZDV) monotherapy, compared with antiretroviral therapy (ART)-naive WLHIV and HIV-negative women. DESIGN: Systematic review and meta-analysis. METHODS: We conducted a systematic li...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://pubmed.ncbi.nlm.nih.gov/35608111
データ提供:米国国立医学図書館(NLM)
Perinatal Outcomes in Pregnant Women Living with HIV: A Meta-Analysis
In the realm of [maternal health], the pursuit of safe and effective treatments for pregnant women living with [HIV] is a constant endeavor. This meta-analysis examines the potential risks and benefits of [antiretroviral therapy (ART)] for pregnant women, focusing on the impact on [perinatal outcomes]. Imagine a pregnant camel traversing a challenging desert, facing the potential risks and uncertainties of her journey. This study delves into the complexities of HIV treatment during pregnancy, seeking to understand the potential impact on the health of both mother and child.
Navigating the Challenges of HIV Treatment During Pregnancy
The study highlights the importance of considering the potential risks and benefits of [HAART] and [zidovudine (ZDV) monotherapy] for pregnant women living with HIV. While ART can effectively suppress viral replication and reduce the risk of [HIV] transmission to the infant, it can also be associated with an increased risk of certain adverse perinatal outcomes, such as [preterm birth], [low birth weight], and [small for gestational age]. These findings emphasize the importance of careful monitoring and management during pregnancy, ensuring that the benefits of ART outweigh any potential risks.
Striving for Optimal Outcomes for Mothers and Infants
This research underscores the need for a comprehensive approach to the care of pregnant women living with HIV, balancing the need for effective viral suppression with the minimization of potential risks to both mother and infant. The study highlights the importance of personalized treatment plans, taking into account individual patient characteristics and factors that may influence perinatal outcomes. It is a reminder that the desert of maternal health is a complex and challenging landscape, requiring a multi-faceted approach to ensure optimal outcomes for both mothers and their infants.
Dr. Camel's Conclusion
This meta-analysis provides valuable insights into the complexities of HIV treatment during pregnancy. It highlights the importance of balancing the benefits and risks of ART, reminding us that the desert of maternal health can be navigated successfully with careful planning and a keen eye for the potential pitfalls. The study underscores the importance of personalized care and ongoing research to optimize outcomes for both mothers and infants living with HIV.
Date :
- Date Completed 2022-07-27
- Date Revised 2022-08-28
Further Info :
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