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Predictors of abstinence, no heavy drinking days, and a 2-level reduction in World Health Organization drinking levels during treatment for alcohol use disorder in the COMBINE study.

Author: GueorguievaRalitza, O'MalleyStephanie S, PhanHuong, WallachJoshua D, WitkiewitzKatie, WuRan

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.

Overview

This study aimed to identify factors that predict how well people with alcohol use disorder (AUD) respond to treatment, regardless of the specific medication they receive. The researchers used data from a large study called COMBINE to determine which characteristics are associated with successful outcomes, such as abstaining from alcohol, reducing heavy drinking days, or making significant reductions in alcohol consumption.
Paper Details　
Original Abstract of the Article :
Data from trials of medications for alcohol use disorder (AUD) can be used to identify predictors of drinking outcomes regardless of treatment, which can inform the design of future trials with heterogeneous populations. Here, we identified predictors of abstinence, no heavy drinking days, and a 2-l...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/35616436

データ提供：米国国立医学図書館（NLM）

Predictors of Alcohol Use Disorder Treatment Success

This study delves into the complex world of alcohol use disorder (AUD) treatment, exploring factors that influence treatment success. Researchers analyzed data from a large clinical trial, the Combined Pharmacotherapies and Behavioral Interventions (COMBINE) Study, to identify predictors of abstinence, reduced heavy drinking days, and improved drinking levels.

Tailoring Treatment to Individual Needs

The findings of this study underscore the importance of understanding the individual factors that influence treatment success. This knowledge can help tailor treatment plans to address the specific needs of each patient, much like adapting a camel caravan route to navigate challenging desert terrain.

Improving Treatment Outcomes

This research is a vital step towards improving treatment outcomes for individuals with AUD. By identifying predictors of success, we can develop more effective strategies to support their recovery journey.

Dr.Camel's Conclusion

This study provides valuable insight into the factors that influence alcohol use disorder treatment success. It is a reminder that we must continue to explore new approaches to tailor treatment to individual needs and improve outcomes.

Date :
  1. Date Completed 2022-08-08
  2. Date Revised 2023-03-25
Further Info :

Pubmed ID

35616436

DOI: Digital Object Identifier

NIHMS1857007

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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